A case of acute lymphoblastic leukemia presenting as severe hypercalcemia

Paola Sabrina Buonuomo; Antonio Ruggiero; Marco Piastra; Riccardo Riccardi; Giancarlo Polidori; Antonio Chiaretti

doi:10.1080/08880010490477248

A case of acute lymphoblastic leukemia presenting as severe hypercalcemia

Paola Sabrina Buonuomo, Antonio Ruggiero, Marco Piastra, Riccardo Riccardi, Giancarlo Polidori, Antonio Chiaretti

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

A 9-year-old girl presented at the Pediatric Emergency Department with an acute onset of gastrointestinal symptoms due to hypercalcemia. Despite the absence of circulating blast, bone marrow biopsy was diagnostic of acute lymphoblastic leukemia. The hypercalcemia was initially treated with intravenous hydration and furosemide, and later on with bisphosphonates. However, the serum calcium levels normalized only after the beginning of specific chemotherapy. Hypercalcemia represents an emergency in children, and acute leukemia must be considered in its differential diagnosis, even when there are no circulating blasts.

Original language	English
Pages (from-to)	475-479
Number of pages	5
Journal	Pediatric Hematology and Oncology
Volume	21
Issue number	6
DOIs	https://doi.org/10.1080/08880010490477248
Publication status	Published - Sep 2004

Keywords

Bisphosphonates
Childhood
Hypercalcemia
Leukemia

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology
Cancer Research

Access to Document

10.1080/08880010490477248

Fingerprint Dive into the research topics of 'A case of acute lymphoblastic leukemia presenting as severe hypercalcemia'. Together they form a unique fingerprint.

Cite this

@article{1341ad8df48448c88d318f6be314a14e,

title = "A case of acute lymphoblastic leukemia presenting as severe hypercalcemia",

abstract = "A 9-year-old girl presented at the Pediatric Emergency Department with an acute onset of gastrointestinal symptoms due to hypercalcemia. Despite the absence of circulating blast, bone marrow biopsy was diagnostic of acute lymphoblastic leukemia. The hypercalcemia was initially treated with intravenous hydration and furosemide, and later on with bisphosphonates. However, the serum calcium levels normalized only after the beginning of specific chemotherapy. Hypercalcemia represents an emergency in children, and acute leukemia must be considered in its differential diagnosis, even when there are no circulating blasts.",

keywords = "Bisphosphonates, Childhood, Hypercalcemia, Leukemia",

author = "Buonuomo, {Paola Sabrina} and Antonio Ruggiero and Marco Piastra and Riccardo Riccardi and Giancarlo Polidori and Antonio Chiaretti",

year = "2004",

month = sep,

doi = "10.1080/08880010490477248",

language = "English",

volume = "21",

pages = "475--479",

journal = "Pediatric Hematology and Oncology",

issn = "0888-0018",

publisher = "Informa Healthcare",

number = "6",

}

TY - JOUR

T1 - A case of acute lymphoblastic leukemia presenting as severe hypercalcemia

AU - Buonuomo, Paola Sabrina

AU - Ruggiero, Antonio

AU - Piastra, Marco

AU - Riccardi, Riccardo

AU - Polidori, Giancarlo

AU - Chiaretti, Antonio

PY - 2004/9

Y1 - 2004/9

N2 - A 9-year-old girl presented at the Pediatric Emergency Department with an acute onset of gastrointestinal symptoms due to hypercalcemia. Despite the absence of circulating blast, bone marrow biopsy was diagnostic of acute lymphoblastic leukemia. The hypercalcemia was initially treated with intravenous hydration and furosemide, and later on with bisphosphonates. However, the serum calcium levels normalized only after the beginning of specific chemotherapy. Hypercalcemia represents an emergency in children, and acute leukemia must be considered in its differential diagnosis, even when there are no circulating blasts.

AB - A 9-year-old girl presented at the Pediatric Emergency Department with an acute onset of gastrointestinal symptoms due to hypercalcemia. Despite the absence of circulating blast, bone marrow biopsy was diagnostic of acute lymphoblastic leukemia. The hypercalcemia was initially treated with intravenous hydration and furosemide, and later on with bisphosphonates. However, the serum calcium levels normalized only after the beginning of specific chemotherapy. Hypercalcemia represents an emergency in children, and acute leukemia must be considered in its differential diagnosis, even when there are no circulating blasts.

KW - Bisphosphonates

KW - Childhood

KW - Hypercalcemia

KW - Leukemia

UR - http://www.scopus.com/inward/record.url?scp=4444279164&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4444279164&partnerID=8YFLogxK

U2 - 10.1080/08880010490477248

DO - 10.1080/08880010490477248

M3 - Article

C2 - 15552810

AN - SCOPUS:4444279164

VL - 21

SP - 475

EP - 479

JO - Pediatric Hematology and Oncology

JF - Pediatric Hematology and Oncology

SN - 0888-0018

IS - 6

ER -