A case of anaplastic thyroid cancer with long-term survival

Haralabos Koussis, Marco Maruzzo, Annamaria Scola, Eric Casal Ide, Ambrogio Fassina, Gino Marioni, Ornella Lora, Luigi Corti, Paraskevi Karachontziti, Antonio Jirillo

Research output: Contribution to journalArticlepeer-review


Anaplastic thyroid carcinoma (ATC) (less than 10% of all thyroid cancer) is a high-grade neoplasm, characterized by an aggressive clinical course and refractoriness to currently available local and systemic modalities of treatment. It is considered the most aggressive solid tumour, there is no adequate therapy for this disease and few patients with ATC live more than 1 year following diagnosis. We report herein an unusual case of ATC in a 59-year-old woman. She presented to our Institute in December 2004. She received many kinds of chemotherapeutical and multimodal treatment; we obtained a long period of localized disease (about two years) and an excellent response to therapy. She is still alive 58 months from diagnosis.

Original languageEnglish
Pages (from-to)1273-1278
Number of pages6
JournalAnticancer Research
Issue number4
Publication statusPublished - Apr 2010


  • Anaplastic thyroid carcinoma
  • Case report
  • Chemotherapy
  • Long-term survival
  • Multimodal treatment

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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