A Case of Coloboma in a Newborn to a Woman Taking Mycophenolate Mofetil in Pregnancy After Kidney Transplantation

M. Framarino dei Malatesta, B. Rocca, T. Gentile, T. Hadjistilianou, M. Borri, S. de Francesco, F. Pisani, A. Famulari

Research output: Contribution to journalArticle

Abstract

Recently, mycophenolate mofetil (MMF) has been introduced in the immunosuppressive strategy after kidney transplantation. Recently, the existence of a MMF associated embriopathy has been hypothesized, namely, multiple craniofacial malformations. Only 1 report has described chorioretinal coloboma. We report a case of woman who used MMF throughout pregnancy after kidney transplantation. Her newborn developed coloboma of the right eye associated with an ocular cyst without any other malformation. The other drugs used by our patient are not considered teratogenic. Therefore, it seems reasonable to conclude a causal relationship between MMF and the malformation observed in this newborn.

Original languageEnglish
Pages (from-to)1407-1409
Number of pages3
JournalTransplantation Proceedings
Volume41
Issue number4
DOIs
Publication statusPublished - May 2009

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Coloboma
Mycophenolic Acid
Kidney Transplantation
Newborn Infant
Pregnancy
Immunosuppressive Agents
Cysts
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Surgery
  • Transplantation
  • Medicine(all)

Cite this

dei Malatesta, M. F., Rocca, B., Gentile, T., Hadjistilianou, T., Borri, M., de Francesco, S., ... Famulari, A. (2009). A Case of Coloboma in a Newborn to a Woman Taking Mycophenolate Mofetil in Pregnancy After Kidney Transplantation. Transplantation Proceedings, 41(4), 1407-1409. https://doi.org/10.1016/j.transproceed.2009.03.088

A Case of Coloboma in a Newborn to a Woman Taking Mycophenolate Mofetil in Pregnancy After Kidney Transplantation. / dei Malatesta, M. Framarino; Rocca, B.; Gentile, T.; Hadjistilianou, T.; Borri, M.; de Francesco, S.; Pisani, F.; Famulari, A.

In: Transplantation Proceedings, Vol. 41, No. 4, 05.2009, p. 1407-1409.

Research output: Contribution to journalArticle

dei Malatesta, MF, Rocca, B, Gentile, T, Hadjistilianou, T, Borri, M, de Francesco, S, Pisani, F & Famulari, A 2009, 'A Case of Coloboma in a Newborn to a Woman Taking Mycophenolate Mofetil in Pregnancy After Kidney Transplantation', Transplantation Proceedings, vol. 41, no. 4, pp. 1407-1409. https://doi.org/10.1016/j.transproceed.2009.03.088
dei Malatesta, M. Framarino ; Rocca, B. ; Gentile, T. ; Hadjistilianou, T. ; Borri, M. ; de Francesco, S. ; Pisani, F. ; Famulari, A. / A Case of Coloboma in a Newborn to a Woman Taking Mycophenolate Mofetil in Pregnancy After Kidney Transplantation. In: Transplantation Proceedings. 2009 ; Vol. 41, No. 4. pp. 1407-1409.
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