A case of congenital dyserythropoietic anemia type II, Gilbert's syndrome and malleolar trophic ulcers

Bruno Bordi, Maria Rosaria D'Amico, Roberto Guariglia, Gaetana Capobianco, Emilio Bordi, Angelo Tirelli

Research output: Contribution to journalArticle

Abstract

A case of a woman with congenital dyserythropoietic anemia type II (CDA-II), Gilbert's syndrome (GS) and trophic malleolar ulceration is described. The association of CDA-II and GS caused early gallstone formation that led the patient to undergo cholecystectomy at the age of 15. GS is typified by increased production of both unconjugated and monoconjugated bilirubin, which is more lithogenic. The development of ulcers is not typical of CDA-II, even though they are associated with many of the hemolytic anemias, and were thought in our patient to be due to a thrombophilic tendency which manifest with Antithrombin III and Protein C deficiency.

Original languageEnglish
Pages (from-to)197-199
Number of pages3
JournalHematology
Volume7
Issue number3
Publication statusPublished - 2002

    Fingerprint

Keywords

  • Congenital dyserythropoietic anemia type II
  • Gallstones
  • Gilbert's syndrome
  • Malleolar ulcers
  • Thrombophilia

ASJC Scopus subject areas

  • Hematology

Cite this

Bordi, B., D'Amico, M. R., Guariglia, R., Capobianco, G., Bordi, E., & Tirelli, A. (2002). A case of congenital dyserythropoietic anemia type II, Gilbert's syndrome and malleolar trophic ulcers. Hematology, 7(3), 197-199.