A case of late onset lipid storage myopathy: Electromyographic histochemical and ultrastructural findings

P. Pinelli, M. Poloni, G. Nappi, R. Scelsi

Research output: Contribution to journalArticlepeer-review

Abstract

A 65-year-old woman showed the clinical picture of a myogenic myopathy, confirmed electromyographically. Detailed histopathological, histochemical and ultrastructural studies were performed on deltoid and quadriceps femoris biopsy specimens. Many muscle fibres were found to contain vacuolar spaces with lipid droplets: perivascular inflammatory changes were also observed. The affected fibres were consistently type I. Under the electron microscope the fibres contained large numbers of lipid droplets, usually next to normal mitochondria. A slight improvement occurred after prednisone therapy.

Original languageEnglish
Pages (from-to)273-284
Number of pages12
JournalEuropean Neurology
Volume13
Issue number3
DOIs
Publication statusPublished - 1975

Keywords

  • Late onset myopathy
  • Lipid storage myopathy
  • Prednisone therapy
  • Type i fibre atrophy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Fingerprint Dive into the research topics of 'A case of late onset lipid storage myopathy: Electromyographic histochemical and ultrastructural findings'. Together they form a unique fingerprint.

Cite this