A case of manic episode during treatment with 5-fluorouracil, epirubicin and cyclophosphamide for breast cancer

Isabella Pacchiarotti; Lorenzo Mazzarini; Patrizia Pellegrini; Viola Venturelli; Gabriele Sani; José Sánchez-Moreno; Iginia Mancinelli; Roberto Tatarelli; Giorgio D. Kotzalidis; Paolo Girardi

doi:10.1016/j.genhosppsych.2007.04.007

A case of manic episode during treatment with 5-fluorouracil, epirubicin and cyclophosphamide for breast cancer

Isabella Pacchiarotti, Lorenzo Mazzarini, Patrizia Pellegrini, Viola Venturelli, Gabriele Sani, José Sánchez-Moreno, Iginia Mancinelli, Roberto Tatarelli, Giorgio D. Kotzalidis, Paolo Girardi

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

A 41-year-old woman with breast cancer developed a manic episode while being treated with a 5-fluorouracil-epirubicin-cyclophosphamide combination (most likely caused by the first drug). Chemotherapy was discontinued, and antipsychotic treatment with haloperidol and olanzapine was instituted. She recovered after 10 days. Normal computerized tomography (CT) scans and neurological examinations were consistent with the absence of neurological symptoms on physical exam.

Original language	English
Pages (from-to)	461-463
Number of pages	3
Journal	General Hospital Psychiatry
Volume	29
Issue number	5
DOIs	https://doi.org/10.1016/j.genhosppsych.2007.04.007
Publication status	Published - Nov 2007

Keywords

5-Fluorouracil
Cyclophosphamide
Drug-induced
Epirubicin
Leukoencephalopathy
Manic episode

ASJC Scopus subject areas

Emergency Medicine
Medicine(all)
Psychiatry and Mental health

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Pacchiarotti, I., Mazzarini, L., Pellegrini, P., Venturelli, V., Sani, G., Sánchez-Moreno, J., Mancinelli, I., Tatarelli, R., Kotzalidis, G. D., & Girardi, P. (2007). A case of manic episode during treatment with 5-fluorouracil, epirubicin and cyclophosphamide for breast cancer. General Hospital Psychiatry, 29(5), 461-463. https://doi.org/10.1016/j.genhosppsych.2007.04.007

A case of manic episode during treatment with 5-fluorouracil, epirubicin and cyclophosphamide for breast cancer. / Pacchiarotti, Isabella; Mazzarini, Lorenzo; Pellegrini, Patrizia; Venturelli, Viola; Sani, Gabriele; Sánchez-Moreno, José; Mancinelli, Iginia; Tatarelli, Roberto; Kotzalidis, Giorgio D.; Girardi, Paolo.

In: General Hospital Psychiatry, Vol. 29, No. 5, 11.2007, p. 461-463.

Research output: Contribution to journal › Article › peer-review

Pacchiarotti, I, Mazzarini, L, Pellegrini, P, Venturelli, V, Sani, G, Sánchez-Moreno, J, Mancinelli, I, Tatarelli, R, Kotzalidis, GD & Girardi, P 2007, 'A case of manic episode during treatment with 5-fluorouracil, epirubicin and cyclophosphamide for breast cancer', General Hospital Psychiatry, vol. 29, no. 5, pp. 461-463. https://doi.org/10.1016/j.genhosppsych.2007.04.007

Pacchiarotti, Isabella ; Mazzarini, Lorenzo ; Pellegrini, Patrizia ; Venturelli, Viola ; Sani, Gabriele ; Sánchez-Moreno, José ; Mancinelli, Iginia ; Tatarelli, Roberto ; Kotzalidis, Giorgio D. ; Girardi, Paolo. / A case of manic episode during treatment with 5-fluorouracil, epirubicin and cyclophosphamide for breast cancer. In: General Hospital Psychiatry. 2007 ; Vol. 29, No. 5. pp. 461-463.

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