A case of neonatal human parechovirus encephalitis with a favourable outcome

Salvatore Renna, Laura Bergamino, Daniela Pirlo, Andrea Rossi, Milena Furione, Antonio Piralla, Monica Mascaretti, Emilio Cristina, Maria Grazia Marazzi, Pasquale Di Pietro

Research output: Contribution to journalArticlepeer-review


Human parechoviruses (HPeVs) are a new family of neurotropic viruses that cause central nervous system (CNS) infections similar to enterovirus (EVs) meningoencephalitis in the neonatal period, resulting in white matter lesions that can be visualized with cranial ultrasonography and magnetic resonance imaging, and correlated to a large spectrum of neurological outcomes. HPeV should be suspected in neonates with signs and symptoms of sepsis-like illness or CNS disease. We report a case of neonatal HPeV encephalitis, diagnosed on the basis of clinical and radiological findings and HPeV RT-PCR, with a good neurological outcome.

Original languageEnglish
Pages (from-to)70-73
Number of pages4
JournalBrain and Development
Issue number1
Publication statusPublished - Jan 2014


  • Enterovirus
  • Magnetic resonance imaging
  • Neonatal encephalitis
  • Parechovirus
  • RT-PCR

ASJC Scopus subject areas

  • Clinical Neurology
  • Developmental Neuroscience
  • Pediatrics, Perinatology, and Child Health


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