A case of pulmonary tuberculosis presenting as diffuse alveolar haemorrhage: Is there a role for anticardiolipin antibodies?

Almerico Marruchella, Angela Corpolongo, Chiara Tommasi, Francesco N. Lauria, Pasquale Narciso

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Diffuse alveolar haemorrhage (DAH) has been rarely reported in association with pulmonary infections.Case Presentation: We report the case of a 43 year old immunocompetent man presenting with dyspnoea, fever and haemoptysis. Chest imaging showed bilateral ground glass opacities. Microbiological and molecular tests were positive for Mycobacterium tuberculosis and treatment with isoniazid, rifampicin, ethambutol and pyrazinamide was successful. In this case the diagnosis of DAH relies on clinical, radiological and endoscopic findings. Routine blood tests documented the presence of anticardiolipin antibodies. In the reported case the diagnostic criteria of antiphospholipid syndrome were not fulfilled.Conclusions: The transient presence of anticardiolipin antibodies in association with an unusual clinical presentation of pulmonary tuberculosis is intriguing although a causal relationship cannot be established.

Original languageEnglish
Article number33
JournalBMC Infectious Diseases
Volume10
DOIs
Publication statusPublished - Feb 20 2010

ASJC Scopus subject areas

  • Infectious Diseases

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