TY - JOUR
T1 - A case of pulmonary tuberculosis presenting as diffuse alveolar haemorrhage
T2 - Is there a role for anticardiolipin antibodies?
AU - Marruchella, Almerico
AU - Corpolongo, Angela
AU - Tommasi, Chiara
AU - Lauria, Francesco N.
AU - Narciso, Pasquale
PY - 2010/2/20
Y1 - 2010/2/20
N2 - Background: Diffuse alveolar haemorrhage (DAH) has been rarely reported in association with pulmonary infections.Case Presentation: We report the case of a 43 year old immunocompetent man presenting with dyspnoea, fever and haemoptysis. Chest imaging showed bilateral ground glass opacities. Microbiological and molecular tests were positive for Mycobacterium tuberculosis and treatment with isoniazid, rifampicin, ethambutol and pyrazinamide was successful. In this case the diagnosis of DAH relies on clinical, radiological and endoscopic findings. Routine blood tests documented the presence of anticardiolipin antibodies. In the reported case the diagnostic criteria of antiphospholipid syndrome were not fulfilled.Conclusions: The transient presence of anticardiolipin antibodies in association with an unusual clinical presentation of pulmonary tuberculosis is intriguing although a causal relationship cannot be established.
AB - Background: Diffuse alveolar haemorrhage (DAH) has been rarely reported in association with pulmonary infections.Case Presentation: We report the case of a 43 year old immunocompetent man presenting with dyspnoea, fever and haemoptysis. Chest imaging showed bilateral ground glass opacities. Microbiological and molecular tests were positive for Mycobacterium tuberculosis and treatment with isoniazid, rifampicin, ethambutol and pyrazinamide was successful. In this case the diagnosis of DAH relies on clinical, radiological and endoscopic findings. Routine blood tests documented the presence of anticardiolipin antibodies. In the reported case the diagnostic criteria of antiphospholipid syndrome were not fulfilled.Conclusions: The transient presence of anticardiolipin antibodies in association with an unusual clinical presentation of pulmonary tuberculosis is intriguing although a causal relationship cannot be established.
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U2 - 10.1186/1471-2334-10-33
DO - 10.1186/1471-2334-10-33
M3 - Article
C2 - 20170532
AN - SCOPUS:77649293008
VL - 10
JO - BMC Infectious Diseases
JF - BMC Infectious Diseases
SN - 1471-2334
M1 - 33
ER -