UN CASO DI GRAVE RITARDO MENTALE CON CARIOTIPO 46, XX, 9q12+

Translated title of the contribution: A case of severe mental retardation with a 46, XX, 9q12+ karyotype

E. Bonioli, L. Fasce, A. Iester, M. G. Vianello

Research output: Contribution to journalArticle

Abstract

A case of mental retardation in a subject with slight signs of deformity is reported. Q band analysis of the karyotype showed extension of band 2 of area 1 of the long arm of chromosome No. 9. Examination of this feature after staining with acridine orange made it clear that this extension was not due to spontaneous DNA denaturation, but was caused by local duplication of chromatin. It is pointed out that such chromatin must be considered as constitutive heterochromatin.

Original languageItalian
Pages (from-to)874-878
Number of pages5
JournalMinerva Pediatrica
Volume27
Issue number14
Publication statusPublished - 1975

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Karyotype
Intellectual Disability
Chromatin
Nucleic Acid Denaturation
Chromosomes, Human, Pair 9
Acridine Orange
Heterochromatin
Staining and Labeling

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Bonioli, E., Fasce, L., Iester, A., & Vianello, M. G. (1975). UN CASO DI GRAVE RITARDO MENTALE CON CARIOTIPO 46, XX, 9q12+. Minerva Pediatrica, 27(14), 874-878.

UN CASO DI GRAVE RITARDO MENTALE CON CARIOTIPO 46, XX, 9q12+. / Bonioli, E.; Fasce, L.; Iester, A.; Vianello, M. G.

In: Minerva Pediatrica, Vol. 27, No. 14, 1975, p. 874-878.

Research output: Contribution to journalArticle

Bonioli, E, Fasce, L, Iester, A & Vianello, MG 1975, 'UN CASO DI GRAVE RITARDO MENTALE CON CARIOTIPO 46, XX, 9q12+', Minerva Pediatrica, vol. 27, no. 14, pp. 874-878.
Bonioli E, Fasce L, Iester A, Vianello MG. UN CASO DI GRAVE RITARDO MENTALE CON CARIOTIPO 46, XX, 9q12+. Minerva Pediatrica. 1975;27(14):874-878.
Bonioli, E. ; Fasce, L. ; Iester, A. ; Vianello, M. G. / UN CASO DI GRAVE RITARDO MENTALE CON CARIOTIPO 46, XX, 9q12+. In: Minerva Pediatrica. 1975 ; Vol. 27, No. 14. pp. 874-878.
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