Carcinoma a piccole cellule della prostata. Descrizione di un caso

Translated title of the contribution: A case of small cell carcinoma of the prostate

Stefano M. Candura, Rodolfo Fonte, Giuseppina Cantale, Donatella Paolotti, Giampiero Biscaldi

Research output: Contribution to journalArticlepeer-review


The case of a 73-year-old man with metastatic small cell carcinoma (SCC) of the prostate is described. Serie neuron-specific enolase (NSE) was enhanced (75.4 ng/mL), while the prostate-specific antigen (PSA) was in the normal range. Therapy with etoposide and carboplatin induced a temporary partial remission, with fairly good quality of life and decrease of the NSE levels (down to 15.0 ng/mL). The patient died approximately 12 months after the initial diagnosis. The case confirms that prostatic SCC (a rare and very aggressive neoplasm) is usually diagnosed in an advanced stage. Treatment is problematic, however chemotherapy may prolong survival allowing, at least temporarly, an acceptable life quality. NSE measurement is useful to differentiate SCC from the more common adenocarcinoma (typically associated with elevated PSA values) and for follow-up.

Translated title of the contributionA case of small cell carcinoma of the prostate
Original languageItalian
Pages (from-to)567-570
Number of pages4
JournalRecenti Progressi in Medicina
Issue number11
Publication statusPublished - Nov 2000

ASJC Scopus subject areas

  • Medicine(all)


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