TY - JOUR
T1 - Carcinoma a piccole cellule della prostata. Descrizione di un caso
AU - Candura, Stefano M.
AU - Fonte, Rodolfo
AU - Cantale, Giuseppina
AU - Paolotti, Donatella
AU - Biscaldi, Giampiero
PY - 2000/11
Y1 - 2000/11
N2 - The case of a 73-year-old man with metastatic small cell carcinoma (SCC) of the prostate is described. Serie neuron-specific enolase (NSE) was enhanced (75.4 ng/mL), while the prostate-specific antigen (PSA) was in the normal range. Therapy with etoposide and carboplatin induced a temporary partial remission, with fairly good quality of life and decrease of the NSE levels (down to 15.0 ng/mL). The patient died approximately 12 months after the initial diagnosis. The case confirms that prostatic SCC (a rare and very aggressive neoplasm) is usually diagnosed in an advanced stage. Treatment is problematic, however chemotherapy may prolong survival allowing, at least temporarly, an acceptable life quality. NSE measurement is useful to differentiate SCC from the more common adenocarcinoma (typically associated with elevated PSA values) and for follow-up.
AB - The case of a 73-year-old man with metastatic small cell carcinoma (SCC) of the prostate is described. Serie neuron-specific enolase (NSE) was enhanced (75.4 ng/mL), while the prostate-specific antigen (PSA) was in the normal range. Therapy with etoposide and carboplatin induced a temporary partial remission, with fairly good quality of life and decrease of the NSE levels (down to 15.0 ng/mL). The patient died approximately 12 months after the initial diagnosis. The case confirms that prostatic SCC (a rare and very aggressive neoplasm) is usually diagnosed in an advanced stage. Treatment is problematic, however chemotherapy may prolong survival allowing, at least temporarly, an acceptable life quality. NSE measurement is useful to differentiate SCC from the more common adenocarcinoma (typically associated with elevated PSA values) and for follow-up.
KW - Neuron-specific enolase
KW - Prostate
KW - Small cell carcinoma
UR - http://www.scopus.com/inward/record.url?scp=0034324173&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034324173&partnerID=8YFLogxK
M3 - Articolo
C2 - 11125949
AN - SCOPUS:0034324173
VL - 91
SP - 567
EP - 570
JO - Recenti Progressi in Medicina
JF - Recenti Progressi in Medicina
SN - 0034-1193
IS - 11
ER -