Abstract
Activating mutations of the RET gene have been described for both papillary (chromosomal rearrangement) and medullary (missense mutations) thyroid carcinomas. Here, we describe a case of a Warthin-like variant of papillary thyroid carcinoma displaying some morphological aspects that mimic the diffuse sclerosing variant. The tumour harboured BRAF V600E mutation and a novel germline point mutation in the RET gene, with unknown clinical and pathological meaning.
Original language | English |
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Article number | 965 |
Journal | ecancermedicalscience |
Volume | 13 |
DOIs | |
Publication status | Published - Oct 2 2019 |
Keywords
- BRAF
- Mutation
- Pathology
- RET
- Thyroid carcinoma
ASJC Scopus subject areas
- Oncology
- Cancer Research