A comparison of GAD- and GABA-immunoreactive neurons in the first somatosensory area (SI) of the rat cortex

R. Spreafico, S. De Biasi, C. Frassoni, G. Battaglia

Research output: Contribution to journalArticle


Neurons immunoreactive for anti-glutamic acid decarboxylase (anti-GAD) and anti-γ-aminobutyric acid (anti-GABA) were compared in adjacent sections from the rat somatosensory cortex (SI). GAD- and GABA-positive neurons in animals either treated or not treated with colchicine were found to occur at a ratio of 1:2. Measurement of areas of GAD- and GABA-immunoreactive neurons confirmed the presence of an 'exuberant' GABA-positive neuronal population not visualized by the GAD antiserum.

Original languageEnglish
Pages (from-to)192-196
Number of pages5
JournalBrain Research
Issue number1
Publication statusPublished - Nov 22 1988



  • Glutamic acid decarboxylase
  • Immunocytochemistry
  • Rat
  • Somatosensory cortex
  • γ-Aminobutyric acid

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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