TY - JOUR
T1 - A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome
AU - Bernasconi, P.
AU - Cavigliano, P. M.
AU - Genini, E.
AU - Castagnola, C.
AU - Malcovati, L.
AU - Calatroni, S.
AU - Caresana, M.
AU - Boni, M.
AU - Alessandrino, E. P.
AU - Astori, C.
AU - Corso, A.
AU - Bernasconi, C.
PY - 1998/9
Y1 - 1998/9
N2 - Complete or partial monosomy for the long arms of chromosomes 5 or 7 or both is frequently observed in therapy-related myelodysplostic syndromes and acute nonlymphocytic leukemia. Sporadic cases have been reported in which partial monosomy is due to unbalanced translocations. The patient described herein carries one such rearrangement, 46,XY,t(1;2)(q32;p23),del(5)(q13),der(7)(5qter→ 5q22::7p15→7q21:),del(12)(p12), resulting in partial monosomy for the long arms of chromosomes 5 and 7 and in partial monosomy for the short arm of chromosome 7.
AB - Complete or partial monosomy for the long arms of chromosomes 5 or 7 or both is frequently observed in therapy-related myelodysplostic syndromes and acute nonlymphocytic leukemia. Sporadic cases have been reported in which partial monosomy is due to unbalanced translocations. The patient described herein carries one such rearrangement, 46,XY,t(1;2)(q32;p23),del(5)(q13),der(7)(5qter→ 5q22::7p15→7q21:),del(12)(p12), resulting in partial monosomy for the long arms of chromosomes 5 and 7 and in partial monosomy for the short arm of chromosome 7.
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U2 - 10.1016/S0165-4608(97)00474-3
DO - 10.1016/S0165-4608(97)00474-3
M3 - Article
C2 - 9723039
AN - SCOPUS:0032171473
VL - 105
SP - 182
EP - 186
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
SN - 0165-4608
IS - 2
ER -