A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome

P. Bernasconi; P. M. Cavigliano; E. Genini; C. Castagnola; L. Malcovati; S. Calatroni; M. Caresana; M. Boni; E. P. Alessandrino; C. Astori; A. Corso; C. Bernasconi

doi:10.1016/S0165-4608(97)00474-3

A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome

P. Bernasconi, P. M. Cavigliano, E. Genini, C. Castagnola, L. Malcovati, S. Calatroni, M. Caresana, M. Boni, E. P. Alessandrino, C. Astori, A. Corso, C. Bernasconi

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Complete or partial monosomy for the long arms of chromosomes 5 or 7 or both is frequently observed in therapy-related myelodysplostic syndromes and acute nonlymphocytic leukemia. Sporadic cases have been reported in which partial monosomy is due to unbalanced translocations. The patient described herein carries one such rearrangement, 46,XY,t(1;2)(q32;p23),del(5)(q13),der(7)(5qter→ 5q22::7p15→7q21:),del(12)(p12), resulting in partial monosomy for the long arms of chromosomes 5 and 7 and in partial monosomy for the short arm of chromosome 7.

Original language	English
Pages (from-to)	182-186
Number of pages	5
Journal	Cancer Genetics and Cytogenetics
Volume	105
Issue number	2
DOIs	https://doi.org/10.1016/S0165-4608(97)00474-3
Publication status	Published - Sep 1998

ASJC Scopus subject areas

Cancer Research
Genetics
Molecular Biology

Access to Document

10.1016/S0165-4608(97)00474-3

Fingerprint Dive into the research topics of 'A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome'. Together they form a unique fingerprint.

Cite this

Bernasconi, P., Cavigliano, P. M., Genini, E., Castagnola, C., Malcovati, L., Calatroni, S., Caresana, M., Boni, M., Alessandrino, E. P., Astori, C., Corso, A., & Bernasconi, C. (1998). A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome. Cancer Genetics and Cytogenetics, 105(2), 182-186. https://doi.org/10.1016/S0165-4608(97)00474-3

A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome. / Bernasconi, P.; Cavigliano, P. M.; Genini, E.; Castagnola, C.; Malcovati, L.; Calatroni, S.; Caresana, M.; Boni, M.; Alessandrino, E. P.; Astori, C.; Corso, A.; Bernasconi, C.

In: Cancer Genetics and Cytogenetics, Vol. 105, No. 2, 09.1998, p. 182-186.

Research output: Contribution to journal › Article › peer-review

Bernasconi, P, Cavigliano, PM, Genini, E, Castagnola, C , Malcovati, L, Calatroni, S, Caresana, M, Boni, M, Alessandrino, EP, Astori, C , Corso, A & Bernasconi, C 1998, 'A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome', Cancer Genetics and Cytogenetics, vol. 105, no. 2, pp. 182-186. https://doi.org/10.1016/S0165-4608(97)00474-3

Bernasconi, P. ; Cavigliano, P. M. ; Genini, E. ; Castagnola, C. ; Malcovati, L. ; Calatroni, S. ; Caresana, M. ; Boni, M. ; Alessandrino, E. P. ; Astori, C. ; Corso, A. ; Bernasconi, C. / A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome. In: Cancer Genetics and Cytogenetics. 1998 ; Vol. 105, No. 2. pp. 182-186.

@article{2744edc427f948058e799f15a5a7e570,

title = "A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome",

abstract = "Complete or partial monosomy for the long arms of chromosomes 5 or 7 or both is frequently observed in therapy-related myelodysplostic syndromes and acute nonlymphocytic leukemia. Sporadic cases have been reported in which partial monosomy is due to unbalanced translocations. The patient described herein carries one such rearrangement, 46,XY,t(1;2)(q32;p23),del(5)(q13),der(7)(5qter→ 5q22::7p15→7q21:),del(12)(p12), resulting in partial monosomy for the long arms of chromosomes 5 and 7 and in partial monosomy for the short arm of chromosome 7.",

author = "P. Bernasconi and Cavigliano, {P. M.} and E. Genini and C. Castagnola and L. Malcovati and S. Calatroni and M. Caresana and M. Boni and Alessandrino, {E. P.} and C. Astori and A. Corso and C. Bernasconi",

year = "1998",

month = sep,

doi = "10.1016/S0165-4608(97)00474-3",

language = "English",

volume = "105",

pages = "182--186",

journal = "Cancer Genetics and Cytogenetics",

issn = "0165-4608",

publisher = "Elsevier Inc.",

number = "2",

}

TY - JOUR

T1 - A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome

AU - Bernasconi, P.

AU - Cavigliano, P. M.

AU - Genini, E.

AU - Castagnola, C.

AU - Malcovati, L.

AU - Calatroni, S.

AU - Caresana, M.

AU - Boni, M.

AU - Alessandrino, E. P.

AU - Astori, C.

AU - Corso, A.

AU - Bernasconi, C.

PY - 1998/9

Y1 - 1998/9

N2 - Complete or partial monosomy for the long arms of chromosomes 5 or 7 or both is frequently observed in therapy-related myelodysplostic syndromes and acute nonlymphocytic leukemia. Sporadic cases have been reported in which partial monosomy is due to unbalanced translocations. The patient described herein carries one such rearrangement, 46,XY,t(1;2)(q32;p23),del(5)(q13),der(7)(5qter→ 5q22::7p15→7q21:),del(12)(p12), resulting in partial monosomy for the long arms of chromosomes 5 and 7 and in partial monosomy for the short arm of chromosome 7.

AB - Complete or partial monosomy for the long arms of chromosomes 5 or 7 or both is frequently observed in therapy-related myelodysplostic syndromes and acute nonlymphocytic leukemia. Sporadic cases have been reported in which partial monosomy is due to unbalanced translocations. The patient described herein carries one such rearrangement, 46,XY,t(1;2)(q32;p23),del(5)(q13),der(7)(5qter→ 5q22::7p15→7q21:),del(12)(p12), resulting in partial monosomy for the long arms of chromosomes 5 and 7 and in partial monosomy for the short arm of chromosome 7.

UR - http://www.scopus.com/inward/record.url?scp=0032171473&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032171473&partnerID=8YFLogxK

U2 - 10.1016/S0165-4608(97)00474-3

DO - 10.1016/S0165-4608(97)00474-3

M3 - Article

C2 - 9723039

AN - SCOPUS:0032171473

VL - 105

SP - 182

EP - 186

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

SN - 0165-4608

IS - 2

ER -