Abstract
We design and manufacture a silicone model of the human aorta, able to mimic both the geometrical and the mechanical properties of physiological individuals, with a specific focus on reproducing the compliance. In fact, while the models available in the literature exhibit an unrealistic compliant behavior, though they are detailed from the geometrical viewpoint, here the goal is to provide an accurate compliant tool for in vitro testing the devices that interface with the vascular system. A parametric design of the aortic model is obtained based on the available literature data, and the model is manufactured with a specific silicone mixture using rapid prototyping and molding techniques. The manufactured prototype has been tested by means of computed tomography scans for evaluating the matching of the mechanical properties with the desired ones. Results show a high degree of adherence between the imposed and the measured compliance values for each main aortic section. Thus, our work proves the feasibility of the approach, and the possibility to manufacture compliant models that reproduce the mechanical behavior of the aorta for in vitro studies.
| Original language | English |
|---|---|
| Pages (from-to) | 21-29 |
| Number of pages | 9 |
| Journal | Medical Engineering and Physics |
| Volume | 59 |
| DOIs | |
| Publication status | Published - Sep 2018 |
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A compliant aortic model for in vitro simulations : Design and manufacturing process. / Marconi, Stefania; Lanzarone, Ettore; van Bogerijen, Guido H W; Conti, Michele; Secchi, Francesco; Trimarchi, Santi; Auricchio, Ferdinando.
In: Medical Engineering and Physics, Vol. 59, 09.2018, p. 21-29.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A compliant aortic model for in vitro simulations
T2 - Design and manufacturing process
AU - Marconi, Stefania
AU - Lanzarone, Ettore
AU - van Bogerijen, Guido H W
AU - Conti, Michele
AU - Secchi, Francesco
AU - Trimarchi, Santi
AU - Auricchio, Ferdinando
N1 - Copyright © 2018 IPEM. Published by Elsevier Ltd. All rights reserved.
PY - 2018/9
Y1 - 2018/9
N2 - We design and manufacture a silicone model of the human aorta, able to mimic both the geometrical and the mechanical properties of physiological individuals, with a specific focus on reproducing the compliance. In fact, while the models available in the literature exhibit an unrealistic compliant behavior, though they are detailed from the geometrical viewpoint, here the goal is to provide an accurate compliant tool for in vitro testing the devices that interface with the vascular system. A parametric design of the aortic model is obtained based on the available literature data, and the model is manufactured with a specific silicone mixture using rapid prototyping and molding techniques. The manufactured prototype has been tested by means of computed tomography scans for evaluating the matching of the mechanical properties with the desired ones. Results show a high degree of adherence between the imposed and the measured compliance values for each main aortic section. Thus, our work proves the feasibility of the approach, and the possibility to manufacture compliant models that reproduce the mechanical behavior of the aorta for in vitro studies.
AB - We design and manufacture a silicone model of the human aorta, able to mimic both the geometrical and the mechanical properties of physiological individuals, with a specific focus on reproducing the compliance. In fact, while the models available in the literature exhibit an unrealistic compliant behavior, though they are detailed from the geometrical viewpoint, here the goal is to provide an accurate compliant tool for in vitro testing the devices that interface with the vascular system. A parametric design of the aortic model is obtained based on the available literature data, and the model is manufactured with a specific silicone mixture using rapid prototyping and molding techniques. The manufactured prototype has been tested by means of computed tomography scans for evaluating the matching of the mechanical properties with the desired ones. Results show a high degree of adherence between the imposed and the measured compliance values for each main aortic section. Thus, our work proves the feasibility of the approach, and the possibility to manufacture compliant models that reproduce the mechanical behavior of the aorta for in vitro studies.
U2 - 10.1016/j.medengphy.2018.04.022
DO - 10.1016/j.medengphy.2018.04.022
M3 - Article
C2 - 30077485
VL - 59
SP - 21
EP - 29
JO - Medical Engineering and Physics
JF - Medical Engineering and Physics
SN - 1350-4533
ER -