A computational study of the hemodynamics after "edge-to-edge" mitral valve repair

A. Redaelli, G. Guadagni, R. Fumero, F. Maisano, O. Alfieri

Research output: Contribution to journalArticlepeer-review


Edge-to-edge mitral valve repair consists in suturing the free edge of the leaflets to re-establish coaptation in prolapsing valves. The leaflets are frequently sutured at the middle and a double orifice valve is created. In order to study the hemodynamic implications, a parametric model of the left heart has been developed. Different valve areas and shapes have been investigated. Results show that the simplified Bernoulli formula provides a good estimation of the pressure drop and that the pressure drop may be predicted on the basis of the pre-operative geometric and hemodynamics data by means of customized models.

Original languageEnglish
Pages (from-to)565-570
Number of pages6
JournalJournal of Biomechanical Engineering
Issue number6
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering


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