A critical review of functional assessment tools for upper limbs in Duchenne muscular dystrophy

Elena S. Mazzone, Gessica Vasco, Concetta Palermo, Flaviana Bianco, Carmen Galluccio, Valeria Ricotti, Antonella D. Castronovo, Maria Sole Di Mauro, Marika Pane, Anna Mayhew, Eugenio Mercuri

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

The recent development of therapeutic approaches for Duchenne muscular dystrophy (DMD) has highlighted the need to identify clinical outcome measures for planned efficacy studies. Although several studies have reported the value of functional scales, timed tests, and measures of endurance aimed at ambulant individuals, less has been done to identify reliable measures of function in individuals who have lost ambulation. The aim of this paper is to provide a critical review of the existing literature on functional measures assessing upper extremity function in DMD. Four observer-rated, performance-based measures and four self-reported scales have been previously used in DMD. Each scale provides useful information but none reflects all the different levels of functional ability in activities of daily living observed in individuals with DMD at different ages.

Original languageEnglish
Pages (from-to)879-885
Number of pages7
JournalDevelopmental Medicine and Child Neurology
Volume54
Issue number10
DOIs
Publication statusPublished - Oct 2012

Fingerprint

Duchenne Muscular Dystrophy
Upper Extremity
Activities of Daily Living
Walking
Outcome Assessment (Health Care)
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience

Cite this

A critical review of functional assessment tools for upper limbs in Duchenne muscular dystrophy. / Mazzone, Elena S.; Vasco, Gessica; Palermo, Concetta; Bianco, Flaviana; Galluccio, Carmen; Ricotti, Valeria; Castronovo, Antonella D.; Mauro, Maria Sole Di; Pane, Marika; Mayhew, Anna; Mercuri, Eugenio.

In: Developmental Medicine and Child Neurology, Vol. 54, No. 10, 10.2012, p. 879-885.

Research output: Contribution to journalArticle

Mazzone, ES, Vasco, G, Palermo, C, Bianco, F, Galluccio, C, Ricotti, V, Castronovo, AD, Mauro, MSD, Pane, M, Mayhew, A & Mercuri, E 2012, 'A critical review of functional assessment tools for upper limbs in Duchenne muscular dystrophy', Developmental Medicine and Child Neurology, vol. 54, no. 10, pp. 879-885. https://doi.org/10.1111/j.1469-8749.2012.04345.x
Mazzone, Elena S. ; Vasco, Gessica ; Palermo, Concetta ; Bianco, Flaviana ; Galluccio, Carmen ; Ricotti, Valeria ; Castronovo, Antonella D. ; Mauro, Maria Sole Di ; Pane, Marika ; Mayhew, Anna ; Mercuri, Eugenio. / A critical review of functional assessment tools for upper limbs in Duchenne muscular dystrophy. In: Developmental Medicine and Child Neurology. 2012 ; Vol. 54, No. 10. pp. 879-885.
@article{fb34d08822d04f9f88d7cdc542c4b9d0,
title = "A critical review of functional assessment tools for upper limbs in Duchenne muscular dystrophy",
abstract = "The recent development of therapeutic approaches for Duchenne muscular dystrophy (DMD) has highlighted the need to identify clinical outcome measures for planned efficacy studies. Although several studies have reported the value of functional scales, timed tests, and measures of endurance aimed at ambulant individuals, less has been done to identify reliable measures of function in individuals who have lost ambulation. The aim of this paper is to provide a critical review of the existing literature on functional measures assessing upper extremity function in DMD. Four observer-rated, performance-based measures and four self-reported scales have been previously used in DMD. Each scale provides useful information but none reflects all the different levels of functional ability in activities of daily living observed in individuals with DMD at different ages.",
author = "Mazzone, {Elena S.} and Gessica Vasco and Concetta Palermo and Flaviana Bianco and Carmen Galluccio and Valeria Ricotti and Castronovo, {Antonella D.} and Mauro, {Maria Sole Di} and Marika Pane and Anna Mayhew and Eugenio Mercuri",
year = "2012",
month = "10",
doi = "10.1111/j.1469-8749.2012.04345.x",
language = "English",
volume = "54",
pages = "879--885",
journal = "Developmental Medicine and Child Neurology",
issn = "0012-1622",
publisher = "Wiley-Blackwell",
number = "10",

}

TY - JOUR

T1 - A critical review of functional assessment tools for upper limbs in Duchenne muscular dystrophy

AU - Mazzone, Elena S.

AU - Vasco, Gessica

AU - Palermo, Concetta

AU - Bianco, Flaviana

AU - Galluccio, Carmen

AU - Ricotti, Valeria

AU - Castronovo, Antonella D.

AU - Mauro, Maria Sole Di

AU - Pane, Marika

AU - Mayhew, Anna

AU - Mercuri, Eugenio

PY - 2012/10

Y1 - 2012/10

N2 - The recent development of therapeutic approaches for Duchenne muscular dystrophy (DMD) has highlighted the need to identify clinical outcome measures for planned efficacy studies. Although several studies have reported the value of functional scales, timed tests, and measures of endurance aimed at ambulant individuals, less has been done to identify reliable measures of function in individuals who have lost ambulation. The aim of this paper is to provide a critical review of the existing literature on functional measures assessing upper extremity function in DMD. Four observer-rated, performance-based measures and four self-reported scales have been previously used in DMD. Each scale provides useful information but none reflects all the different levels of functional ability in activities of daily living observed in individuals with DMD at different ages.

AB - The recent development of therapeutic approaches for Duchenne muscular dystrophy (DMD) has highlighted the need to identify clinical outcome measures for planned efficacy studies. Although several studies have reported the value of functional scales, timed tests, and measures of endurance aimed at ambulant individuals, less has been done to identify reliable measures of function in individuals who have lost ambulation. The aim of this paper is to provide a critical review of the existing literature on functional measures assessing upper extremity function in DMD. Four observer-rated, performance-based measures and four self-reported scales have been previously used in DMD. Each scale provides useful information but none reflects all the different levels of functional ability in activities of daily living observed in individuals with DMD at different ages.

UR - http://www.scopus.com/inward/record.url?scp=84866424753&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84866424753&partnerID=8YFLogxK

U2 - 10.1111/j.1469-8749.2012.04345.x

DO - 10.1111/j.1469-8749.2012.04345.x

M3 - Article

VL - 54

SP - 879

EP - 885

JO - Developmental Medicine and Child Neurology

JF - Developmental Medicine and Child Neurology

SN - 0012-1622

IS - 10

ER -