A cross-correlated experimental set-up for probing normal and abnormal vital processes that are endogenous or induced by xenobiotic agents

M. Milani, M. Ballerini, L. Ferraro, M. Berden Zrimec, A. Zrimec, L. Drinovec, L. Brizhik, F. Causa, A. Oldani, A. Pasinetti, M. Barberis, M. Cannone

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A wealth of data point to Delayed Luminescence (DL) as a good candidate for early and reliable detection technique in neoplastic cells and tissues sorting. Aiming at a DL experimental set up for such a kind of information, a testing technique for morphological analysis should be provided. As such, a strong link among others was reported to exist between DL signal characteristics and cytoskeleton structure and dynamics: Focused Ion Beam (FIB) imaging was for the moment being the best non invasive check at all and it can detect morphological alterations as early as possible since its resolution can go down to 2-5 nm.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsA.-C. Boccara
Pages250-261
Number of pages12
Volume5143
Publication statusPublished - 2003
EventNovel Optical Instrumentation for Biomedical Applications - Munich, Germany
Duration: Jun 24 2003Jun 25 2003

Other

OtherNovel Optical Instrumentation for Biomedical Applications
CountryGermany
CityMunich
Period6/24/036/25/03

Keywords

  • Cell metabolism
  • Confocal microscopy
  • Delayed luminescence
  • Focused ion beam
  • Neoplastic cells

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

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