Studio trasversale multicentrico Europeo su esposizione a basse dosi di benzene

Translated title of the contribution: A cross-sectional multicentre European study on low level exposure to benzene

F. Merlo, P. A. Bertazzi, C. Bolognesi, A. Colombi, S. Fustinoni, M. Buratti, P. Farmer, S. Garte, L. Levy, A. C. Pesatori, T. Popov, E. Taioli, F. Valerio, D. Consonni

Research output: Contribution to journalArticlepeer-review

Abstract

A cross-sectional multicenter european study has been carried out to evacuate the relations between exposure to low level of benzene and biological markers of internal dose (t,t-MA, S-PMA) and early biological effect (DNA-SSB). The research has shown significantly increased levels (adjusted for smoking habits) of the urinary excretion of t,t-MA, S-PMA and DNA-SSB in petrochemical workers (mean benzene level = 5,694 μg/m3) but not in filling station attendants, traffic police officers, and bus drivers compared to referent workers. Dose-response relations were detected between benzene air levels, t,t-MA, S-PMA and DNA-SSB in petrochemical workers, with significantly increased levels of DNA-SSB detected for benzene exposure levels in the range 391-1,800 μg/m3 (0.12-0.58 ppm).

Translated title of the contributionA cross-sectional multicentre European study on low level exposure to benzene
Original languageItalian
Pages (from-to)296-297
Number of pages2
JournalGiornale Italiano di Medicina del Lavoro ed Ergonomia
Volume25
Issue number3
Publication statusPublished - Jul 2003

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Rehabilitation

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