A cross-sectional nationwide survey on esophageal atresia and tracheoesophageal fistula

A. Pini Prato, M. Carlucci, P. Bagolan, P. G. Gamba, M. Bernardi, E. Leva, G. Paradies, C. Manzoni, B. Noccioli, A. Tramontano, V. Jasonni, F. Vaccarella, S. De Pascale, D. Alberti, G. Riccipetitoni, D. Falchetti, F. Caccia, G. Pelizzo, J. Schleef, M. LimaP. Andriolo, A. Franchella, A. Cacciari, F. Caravaggi, S. Federici, M. Andermarcher, G. Perrino, D. Codrich, F. S. Camoglio, F. S. Chiarenza, A. Martino, A. Appignani, V. Briganti, S. Caterino, D. Cozzi, M. Messina, A. Rizzo, L. Liotta, D. Salerno, M. G R Aceti, F. Bartoli, C. Romeo, C. Esposito, P. L. Lelli Chiesa, E. Clemente, L. Mascia, S. Cacciaguerra, V. Di Benedetto, S. Licciardi, E. De Grazia, M. Ubertazzi, G. Piazza, G. Mattioli, F. Rossi, M. Nobili

Research output: Contribution to journalArticlepeer-review


Background Our study aims at disclosing epidemiology and most relevant clinical features of esophageal atresia (EA) pointing to a model of multicentre collaboration. Methods A detailed questionnaire was sent to all Italian Units of pediatric surgery in order to collect data of patients born with EA between January and December 2012. The results were crosschecked by matching date and place of birth of the patients with those of diagnosis-related group provided by the Italian Ministry of Health (MOH). Results A total of 146 questionnaires were returned plus a further 32 patients reported in the MOH database. Basing on a total of 178 patients with EA born in Italy in 2012, the incidence of EA was calculated in 3.33 per 10,000 live births. Antenatal diagnosis was suspected in 29.5% patients. 55.5% showed associated anomalies. The most common type of EA was Gross type C (89%). Postoperative complications occurred in 37% of type C EA and 100% of type A EA. A 9.5% mortality rate was reported. Conclusions This is the first Italian cross-sectional nationwide survey on EA. We can now develop shared guidelines and provide more reliable prognostic expectations for our patients.

Original languageEnglish
Pages (from-to)1441-1456
Number of pages16
JournalJournal of Pediatric Surgery
Issue number9
Publication statusPublished - Sep 1 2015


  • Cross-sectional
  • Diagnosis
  • Key words Esophageal atresia
  • Management
  • Mortality
  • Nationwide survey

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health


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