Abstract
Summary We report two cases of factor V deficiency. A 12‐year‐old girl with thalassemia major was admitted for bone marrow transplant (mismatched). She was found to have a heterozygous deficiency of factor V (21%), but this was considered compatible with the transplant, which was performed without the support of suppernatant cryoprecipitate. A 14‐year‐old girl (factor V 2%) with a negative history (menarche at age 12, menstrual cycle regular and normal in quantity and length). One year previously she had complained of menorrhagia (length of period, 9 days); tests revealed server anaemia (Hb 4.9 g/dl). We show how even severe cases of factor V deficiency may often be silent, and not require transfusion in surgical procedures, thus avoiding the risks associated with such therapy.
Original language | English |
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Pages (from-to) | 200-201 |
Number of pages | 2 |
Journal | Haemophilia |
Volume | 1 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1995 |
Keywords
- bone marrow transplant
- coagulation tests
- factor V
- factor V deficiency
- menorrhagia
- parahaemophilia
ASJC Scopus subject areas
- Genetics(clinical)
- Hematology