A dopamine stimulated adenylate cyclase in rat substantia nigra

P. F. Spano, G. Di Chiara, G. C. Tonon, M. Trabucchi

Research output: Contribution to journalArticlepeer-review

Abstract

In this study the authors have found than an adenylate cyclase which is preferentially stimulated by dopamine is present in the substantia nigra of rat brain. We suggest that the dopamine stimulated adenylate cyclase of substantia nigra may be part of a receptor mechanism for the pool of dopamine released from the dendrites of dopaminergic neurons. Therefore, the dopamine stimulated adenylate cyclase of the substantia nigra may provide a highly specific model for studying dopamine receptor function in this area.

Original languageEnglish
Pages (from-to)1565-1568
Number of pages4
JournalJournal of Neurochemistry
Volume27
Issue number6
Publication statusPublished - 1976

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

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