In this study the authors have found than an adenylate cyclase which is preferentially stimulated by dopamine is present in the substantia nigra of rat brain. We suggest that the dopamine stimulated adenylate cyclase of substantia nigra may be part of a receptor mechanism for the pool of dopamine released from the dendrites of dopaminergic neurons. Therefore, the dopamine stimulated adenylate cyclase of the substantia nigra may provide a highly specific model for studying dopamine receptor function in this area.
|Number of pages||4|
|Journal||Journal of Neurochemistry|
|Publication status||Published - 1976|
ASJC Scopus subject areas
- Cellular and Molecular Neuroscience