A double blind clinical trial on the effectiveness of a thymic derivative (thymomodulin) in the treatment of children with atopic dermatitis

A. Fiocchi, U. Grasso, A. Rottoli, P. Travaglini, P. Mazzanti, P. Cazzola, M. Giovannini

Research output: Contribution to journalArticle

Abstract

Since atopic dermatitis (AD) occurs in patients with different altered immunological responses, the authors treated this condition with a calf thymus acid lysate (thymomodulin) with immunomodulating properties. Twelve children affected with AD, which was not responsive to dietary restrictions, were randomly assigned to thymomodulin (A) or placebo (B) group in a double-blind trial. Group A received 3 mg/kg/day of thymomodulin syrup. After 6 months of treatment, an improvement of the skin lesions (extension and grade of intensity) was observed only in the thymomodulin group (p

Original languageEnglish
Pages (from-to)279-284
Number of pages6
JournalInternational Journal of Immunotherapy
Volume3
Issue number4
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Immunology

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