A family study of schizotypal disorder

Marco Battaglia; Luana Bernardeschi; Linda Franchini; Laura Bellodi; Enrico Smeraldi

doi:10.1093/schbul/21.1.33

A family study of schizotypal disorder

Marco Battaglia, Luana Bernardeschi, Linda Franchini, Laura Bellodi, Enrico Smeraldi

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article

Abstract

Direct, blind interviews were used to study the risk for and prevalence of DSM-III-R Axis I and II disorders in 93 first-degree relatives of outpatients with schizotypal personality disorder (SPD) and outpatients with other personality disorders. Risks for SPD (at a slightly loosened diagnostic threshold) and schizoid personality disorder were significantly higher in the families of probands with SPD. Schizophrenia was present only among relatives of probands with SPD, accounting for a morbid risk of 4.1 percent. Neither familial risks for mood and anxiety disorders nor the prevalence of other Axis II disorders significantly differed in the two groups of relatives. It is suggested that SPD is a familial disorder representing a phenotypic expression of liability to schizophrenia.

Original language	English
Pages (from-to)	33-45
Number of pages	13
Journal	Schizophrenia Bulletin
Volume	21
Issue number	1
DOIs	https://doi.org/10.1093/schbul/21.1.33
Publication status	Published - 1995

ASJC Scopus subject areas

Statistics, Probability and Uncertainty
Applied Mathematics
Public Health, Environmental and Occupational Health
Radiation
Radiological and Ultrasound Technology
Psychiatry and Mental health
Neuroscience(all)

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Battaglia, M., Bernardeschi, L., Franchini, L., Bellodi, L., & Smeraldi, E. (1995). A family study of schizotypal disorder. Schizophrenia Bulletin, 21(1), 33-45. https://doi.org/10.1093/schbul/21.1.33

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