A prospective study on the association between human Papillomavirus types 16 and 18 infections and cervical neoplasia by morphological analyses and molecular hybridizations was started in May 1988. 212 patients unaffected by genital malignancies have been enrolled in a follow-up program. Regression of HPV 16/18 disease occurred in more than half of the cases. About a third of the patients with HPV 16/18 latent infections developed viral atypia and 4% mild-moderate dysplasia. Progression to severe dysplasia seems to be associated with HPV 16/18 infections.
|Number of pages||4|
|Journal||Journal of Experimental and Clinical Cancer Research|
|Publication status||Published - 1992|
ASJC Scopus subject areas
- Cancer Research