A foregut cystic neoplasm with diagnostic and therapeutic similarities to mucinous cystic neoplasms of the pancreas

Michael D. Kluger, Claude Tayar, Andrea Belli, Juan A. Salceda, Jeanne T. van Nhieu, Alain Luciani, Daniel Cherqui

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Context Greater utilization of cross-sectional abdominal imaging has increased the diagnostic frequency of cystic neoplasms of the pancreas. The "International Consensus Guidelines 2012 for the Management of IPMN and MCN of the Pancreas" illustrates a diagnostic and therapeutic algorithm for these lesions based on current knowledge. Case report We present a case of a 49-year-old woman with two years of intermittent epigastric pain found to have an 8.5 cm head of the pancreas mass on CT. Evaluation was consistent with a mucinous cystic neoplasm for which she underwent an uneventful pancreaticoduodenectomy. Histology revealed a bronchogenic cyst of the head of the pancreas. Discussion Bronchogenic cysts are congenital anomalies of the ventral foregut that can migrate into the abdomen prior to fusion of the diaphragm. They can easily be misdiagnosed for other benign and malignant retroperitoneal lesions. Similarly to mucinous cystic neoplasms, bronchogenic cysts have been reported to undergo malignant transformation. They can also become infected and hemorrhage. Therefore, resection should be performed in appropriate risk candidates. It is possible, with increased use of high resolution cross-sectional imaging, that these lesions may be identified with greater frequency in the abdomen and confused with other pancreatic neoplasms. The presence of ciliated respiratory epithelium and cartilage on pathology provides for definitive diagnosis.

Original languageEnglish
Pages (from-to)446-449
Number of pages4
JournalJournal of the Pancreas
Volume14
Issue number4
Publication statusPublished - 2013

Fingerprint

Bronchogenic Cyst
Pancreatic Neoplasms
Pancreas
Abdomen
Respiratory Mucosa
Neoplasms
Pancreaticoduodenectomy
Diaphragm
Diagnostic Errors
Cartilage
Consensus
Histology
Therapeutics
Guidelines
Pathology
Hemorrhage
Pain

Keywords

  • And serous
  • Bronchogenic cyst
  • Cystic
  • Mucinous
  • Neoplasms
  • Pancreatic neoplasms

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Hepatology

Cite this

Kluger, M. D., Tayar, C., Belli, A., Salceda, J. A., van Nhieu, J. T., Luciani, A., & Cherqui, D. (2013). A foregut cystic neoplasm with diagnostic and therapeutic similarities to mucinous cystic neoplasms of the pancreas. Journal of the Pancreas, 14(4), 446-449.

A foregut cystic neoplasm with diagnostic and therapeutic similarities to mucinous cystic neoplasms of the pancreas. / Kluger, Michael D.; Tayar, Claude; Belli, Andrea; Salceda, Juan A.; van Nhieu, Jeanne T.; Luciani, Alain; Cherqui, Daniel.

In: Journal of the Pancreas, Vol. 14, No. 4, 2013, p. 446-449.

Research output: Contribution to journalArticle

Kluger, MD, Tayar, C, Belli, A, Salceda, JA, van Nhieu, JT, Luciani, A & Cherqui, D 2013, 'A foregut cystic neoplasm with diagnostic and therapeutic similarities to mucinous cystic neoplasms of the pancreas', Journal of the Pancreas, vol. 14, no. 4, pp. 446-449.
Kluger MD, Tayar C, Belli A, Salceda JA, van Nhieu JT, Luciani A et al. A foregut cystic neoplasm with diagnostic and therapeutic similarities to mucinous cystic neoplasms of the pancreas. Journal of the Pancreas. 2013;14(4):446-449.
Kluger, Michael D. ; Tayar, Claude ; Belli, Andrea ; Salceda, Juan A. ; van Nhieu, Jeanne T. ; Luciani, Alain ; Cherqui, Daniel. / A foregut cystic neoplasm with diagnostic and therapeutic similarities to mucinous cystic neoplasms of the pancreas. In: Journal of the Pancreas. 2013 ; Vol. 14, No. 4. pp. 446-449.
@article{2c0a71f341d0402f9a5d5a0d542d6ffc,
title = "A foregut cystic neoplasm with diagnostic and therapeutic similarities to mucinous cystic neoplasms of the pancreas",
abstract = "Context Greater utilization of cross-sectional abdominal imaging has increased the diagnostic frequency of cystic neoplasms of the pancreas. The {"}International Consensus Guidelines 2012 for the Management of IPMN and MCN of the Pancreas{"} illustrates a diagnostic and therapeutic algorithm for these lesions based on current knowledge. Case report We present a case of a 49-year-old woman with two years of intermittent epigastric pain found to have an 8.5 cm head of the pancreas mass on CT. Evaluation was consistent with a mucinous cystic neoplasm for which she underwent an uneventful pancreaticoduodenectomy. Histology revealed a bronchogenic cyst of the head of the pancreas. Discussion Bronchogenic cysts are congenital anomalies of the ventral foregut that can migrate into the abdomen prior to fusion of the diaphragm. They can easily be misdiagnosed for other benign and malignant retroperitoneal lesions. Similarly to mucinous cystic neoplasms, bronchogenic cysts have been reported to undergo malignant transformation. They can also become infected and hemorrhage. Therefore, resection should be performed in appropriate risk candidates. It is possible, with increased use of high resolution cross-sectional imaging, that these lesions may be identified with greater frequency in the abdomen and confused with other pancreatic neoplasms. The presence of ciliated respiratory epithelium and cartilage on pathology provides for definitive diagnosis.",
keywords = "And serous, Bronchogenic cyst, Cystic, Mucinous, Neoplasms, Pancreatic neoplasms",
author = "Kluger, {Michael D.} and Claude Tayar and Andrea Belli and Salceda, {Juan A.} and {van Nhieu}, {Jeanne T.} and Alain Luciani and Daniel Cherqui",
year = "2013",
language = "English",
volume = "14",
pages = "446--449",
journal = "Journal of the Pancreas",
issn = "1590-8577",
publisher = "E.S. Burioni Ricerche Bibliografiche",
number = "4",

}

TY - JOUR

T1 - A foregut cystic neoplasm with diagnostic and therapeutic similarities to mucinous cystic neoplasms of the pancreas

AU - Kluger, Michael D.

AU - Tayar, Claude

AU - Belli, Andrea

AU - Salceda, Juan A.

AU - van Nhieu, Jeanne T.

AU - Luciani, Alain

AU - Cherqui, Daniel

PY - 2013

Y1 - 2013

N2 - Context Greater utilization of cross-sectional abdominal imaging has increased the diagnostic frequency of cystic neoplasms of the pancreas. The "International Consensus Guidelines 2012 for the Management of IPMN and MCN of the Pancreas" illustrates a diagnostic and therapeutic algorithm for these lesions based on current knowledge. Case report We present a case of a 49-year-old woman with two years of intermittent epigastric pain found to have an 8.5 cm head of the pancreas mass on CT. Evaluation was consistent with a mucinous cystic neoplasm for which she underwent an uneventful pancreaticoduodenectomy. Histology revealed a bronchogenic cyst of the head of the pancreas. Discussion Bronchogenic cysts are congenital anomalies of the ventral foregut that can migrate into the abdomen prior to fusion of the diaphragm. They can easily be misdiagnosed for other benign and malignant retroperitoneal lesions. Similarly to mucinous cystic neoplasms, bronchogenic cysts have been reported to undergo malignant transformation. They can also become infected and hemorrhage. Therefore, resection should be performed in appropriate risk candidates. It is possible, with increased use of high resolution cross-sectional imaging, that these lesions may be identified with greater frequency in the abdomen and confused with other pancreatic neoplasms. The presence of ciliated respiratory epithelium and cartilage on pathology provides for definitive diagnosis.

AB - Context Greater utilization of cross-sectional abdominal imaging has increased the diagnostic frequency of cystic neoplasms of the pancreas. The "International Consensus Guidelines 2012 for the Management of IPMN and MCN of the Pancreas" illustrates a diagnostic and therapeutic algorithm for these lesions based on current knowledge. Case report We present a case of a 49-year-old woman with two years of intermittent epigastric pain found to have an 8.5 cm head of the pancreas mass on CT. Evaluation was consistent with a mucinous cystic neoplasm for which she underwent an uneventful pancreaticoduodenectomy. Histology revealed a bronchogenic cyst of the head of the pancreas. Discussion Bronchogenic cysts are congenital anomalies of the ventral foregut that can migrate into the abdomen prior to fusion of the diaphragm. They can easily be misdiagnosed for other benign and malignant retroperitoneal lesions. Similarly to mucinous cystic neoplasms, bronchogenic cysts have been reported to undergo malignant transformation. They can also become infected and hemorrhage. Therefore, resection should be performed in appropriate risk candidates. It is possible, with increased use of high resolution cross-sectional imaging, that these lesions may be identified with greater frequency in the abdomen and confused with other pancreatic neoplasms. The presence of ciliated respiratory epithelium and cartilage on pathology provides for definitive diagnosis.

KW - And serous

KW - Bronchogenic cyst

KW - Cystic

KW - Mucinous

KW - Neoplasms

KW - Pancreatic neoplasms

UR - http://www.scopus.com/inward/record.url?scp=84880067091&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880067091&partnerID=8YFLogxK

M3 - Article

VL - 14

SP - 446

EP - 449

JO - Journal of the Pancreas

JF - Journal of the Pancreas

SN - 1590-8577

IS - 4

ER -