A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis

S. Lekamwasam, J. D. Adachi, D. Agnusdei, J. Bilezikian, S. Boonen, F. Borgström, C. Cooper, A. Diez Perez, R. Eastell, L. C. Hofbauer, J. A. Kanis, B. L. Langdahl, O. Lesnyak, R. Lorenc, E. McCloskey, O. D. Messina, N. Napoli, B. Obermayer-Pietsch, S. H. Ralston, P. N. SambrookS. Silverman, M. Sosa, J. Stepan, G. Suppan, D. A. Wahl, J. E. Compston

Research output: Contribution to journalArticle

180 Citations (Scopus)

Abstract

Summary This paper provides a framework for the development of national guidelines for the management of glucocorticoid- induced osteoporosis in men and women aged 18 years and over in whom oral glucocorticoid therapy is considered for 3 months or longer. Introduction The need for updated guidelines for Europe and other parts of the world was recognised by the International Osteoporosis Foundation and the European Calcified Tissue Society, which set up a joint Guideline Working Group at the end of 2010. Methods and results The epidemiology of GIO is reviewed. Assessment of risk used a fracture probability-based approach, and intervention thresholds were based on 10-year probabilities using FRAX. The efficacy of intervention was assessed by a systematic review.Conclusions Guidance for glucocorticoid-induced osteoporosis is updated in the light of new treatments and methods of assessment. National guidelines derived from this resource need to be tailored within the national healthcare framework of each country.

Original languageEnglish
Pages (from-to)2257-2276
Number of pages20
JournalOsteoporosis International
Volume23
Issue number9
DOIs
Publication statusPublished - Sep 2012

Fingerprint

Glucocorticoids
Osteoporosis
Guidelines
Epidemiology
Joints
Delivery of Health Care
Therapeutics

Keywords

  • Bone mineral density
  • Bone-protective therapy
  • Fracture
  • FRAX
  • Glucocorticoids

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

Cite this

Lekamwasam, S., Adachi, J. D., Agnusdei, D., Bilezikian, J., Boonen, S., Borgström, F., ... Compston, J. E. (2012). A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis. Osteoporosis International, 23(9), 2257-2276. https://doi.org/10.1007/s00198-012-1958-1

A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis. / Lekamwasam, S.; Adachi, J. D.; Agnusdei, D.; Bilezikian, J.; Boonen, S.; Borgström, F.; Cooper, C.; Perez, A. Diez; Eastell, R.; Hofbauer, L. C.; Kanis, J. A.; Langdahl, B. L.; Lesnyak, O.; Lorenc, R.; McCloskey, E.; Messina, O. D.; Napoli, N.; Obermayer-Pietsch, B.; Ralston, S. H.; Sambrook, P. N.; Silverman, S.; Sosa, M.; Stepan, J.; Suppan, G.; Wahl, D. A.; Compston, J. E.

In: Osteoporosis International, Vol. 23, No. 9, 09.2012, p. 2257-2276.

Research output: Contribution to journalArticle

Lekamwasam, S, Adachi, JD, Agnusdei, D, Bilezikian, J, Boonen, S, Borgström, F, Cooper, C, Perez, AD, Eastell, R, Hofbauer, LC, Kanis, JA, Langdahl, BL, Lesnyak, O, Lorenc, R, McCloskey, E, Messina, OD, Napoli, N, Obermayer-Pietsch, B, Ralston, SH, Sambrook, PN, Silverman, S, Sosa, M, Stepan, J, Suppan, G, Wahl, DA & Compston, JE 2012, 'A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis', Osteoporosis International, vol. 23, no. 9, pp. 2257-2276. https://doi.org/10.1007/s00198-012-1958-1
Lekamwasam, S. ; Adachi, J. D. ; Agnusdei, D. ; Bilezikian, J. ; Boonen, S. ; Borgström, F. ; Cooper, C. ; Perez, A. Diez ; Eastell, R. ; Hofbauer, L. C. ; Kanis, J. A. ; Langdahl, B. L. ; Lesnyak, O. ; Lorenc, R. ; McCloskey, E. ; Messina, O. D. ; Napoli, N. ; Obermayer-Pietsch, B. ; Ralston, S. H. ; Sambrook, P. N. ; Silverman, S. ; Sosa, M. ; Stepan, J. ; Suppan, G. ; Wahl, D. A. ; Compston, J. E. / A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis. In: Osteoporosis International. 2012 ; Vol. 23, No. 9. pp. 2257-2276.
@article{55f430c8da044490a10476e6805708bc,
title = "A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis",
abstract = "Summary This paper provides a framework for the development of national guidelines for the management of glucocorticoid- induced osteoporosis in men and women aged 18 years and over in whom oral glucocorticoid therapy is considered for 3 months or longer. Introduction The need for updated guidelines for Europe and other parts of the world was recognised by the International Osteoporosis Foundation and the European Calcified Tissue Society, which set up a joint Guideline Working Group at the end of 2010. Methods and results The epidemiology of GIO is reviewed. Assessment of risk used a fracture probability-based approach, and intervention thresholds were based on 10-year probabilities using FRAX. The efficacy of intervention was assessed by a systematic review.Conclusions Guidance for glucocorticoid-induced osteoporosis is updated in the light of new treatments and methods of assessment. National guidelines derived from this resource need to be tailored within the national healthcare framework of each country.",
keywords = "Bone mineral density, Bone-protective therapy, Fracture, FRAX, Glucocorticoids",
author = "S. Lekamwasam and Adachi, {J. D.} and D. Agnusdei and J. Bilezikian and S. Boonen and F. Borgstr{\"o}m and C. Cooper and Perez, {A. Diez} and R. Eastell and Hofbauer, {L. C.} and Kanis, {J. A.} and Langdahl, {B. L.} and O. Lesnyak and R. Lorenc and E. McCloskey and Messina, {O. D.} and N. Napoli and B. Obermayer-Pietsch and Ralston, {S. H.} and Sambrook, {P. N.} and S. Silverman and M. Sosa and J. Stepan and G. Suppan and Wahl, {D. A.} and Compston, {J. E.}",
year = "2012",
month = "9",
doi = "10.1007/s00198-012-1958-1",
language = "English",
volume = "23",
pages = "2257--2276",
journal = "Osteoporosis International",
issn = "0937-941X",
publisher = "Springer London",
number = "9",

}

TY - JOUR

T1 - A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis

AU - Lekamwasam, S.

AU - Adachi, J. D.

AU - Agnusdei, D.

AU - Bilezikian, J.

AU - Boonen, S.

AU - Borgström, F.

AU - Cooper, C.

AU - Perez, A. Diez

AU - Eastell, R.

AU - Hofbauer, L. C.

AU - Kanis, J. A.

AU - Langdahl, B. L.

AU - Lesnyak, O.

AU - Lorenc, R.

AU - McCloskey, E.

AU - Messina, O. D.

AU - Napoli, N.

AU - Obermayer-Pietsch, B.

AU - Ralston, S. H.

AU - Sambrook, P. N.

AU - Silverman, S.

AU - Sosa, M.

AU - Stepan, J.

AU - Suppan, G.

AU - Wahl, D. A.

AU - Compston, J. E.

PY - 2012/9

Y1 - 2012/9

N2 - Summary This paper provides a framework for the development of national guidelines for the management of glucocorticoid- induced osteoporosis in men and women aged 18 years and over in whom oral glucocorticoid therapy is considered for 3 months or longer. Introduction The need for updated guidelines for Europe and other parts of the world was recognised by the International Osteoporosis Foundation and the European Calcified Tissue Society, which set up a joint Guideline Working Group at the end of 2010. Methods and results The epidemiology of GIO is reviewed. Assessment of risk used a fracture probability-based approach, and intervention thresholds were based on 10-year probabilities using FRAX. The efficacy of intervention was assessed by a systematic review.Conclusions Guidance for glucocorticoid-induced osteoporosis is updated in the light of new treatments and methods of assessment. National guidelines derived from this resource need to be tailored within the national healthcare framework of each country.

AB - Summary This paper provides a framework for the development of national guidelines for the management of glucocorticoid- induced osteoporosis in men and women aged 18 years and over in whom oral glucocorticoid therapy is considered for 3 months or longer. Introduction The need for updated guidelines for Europe and other parts of the world was recognised by the International Osteoporosis Foundation and the European Calcified Tissue Society, which set up a joint Guideline Working Group at the end of 2010. Methods and results The epidemiology of GIO is reviewed. Assessment of risk used a fracture probability-based approach, and intervention thresholds were based on 10-year probabilities using FRAX. The efficacy of intervention was assessed by a systematic review.Conclusions Guidance for glucocorticoid-induced osteoporosis is updated in the light of new treatments and methods of assessment. National guidelines derived from this resource need to be tailored within the national healthcare framework of each country.

KW - Bone mineral density

KW - Bone-protective therapy

KW - Fracture

KW - FRAX

KW - Glucocorticoids

UR - http://www.scopus.com/inward/record.url?scp=84867098592&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84867098592&partnerID=8YFLogxK

U2 - 10.1007/s00198-012-1958-1

DO - 10.1007/s00198-012-1958-1

M3 - Article

C2 - 22434203

AN - SCOPUS:84867098592

VL - 23

SP - 2257

EP - 2276

JO - Osteoporosis International

JF - Osteoporosis International

SN - 0937-941X

IS - 9

ER -