We report the case of a girl with a severe perianal fistulizing Crohn's disease who during intravenous infusion of cyclosporine developed headache, general seizures and cortical blindness. Head magnetic resonance imaging showed spread, cortical-subcortical nonenhancing signal changes. Full neurological recovery was achieved in 24 hours. Cyclosporine was stopped and a single dose of infliximab was infused with rapid improvement of the fistula that at 7 months' follow-up is still closed.
|Number of pages||3|
|Journal||Digestive and Liver Disease|
|Publication status||Published - 2000|
- Cyclosporine-related neurotoxicity
- Fistulizing Crohn's disease
ASJC Scopus subject areas