Abstract
We report the case of a girl with a severe perianal fistulizing Crohn's disease who during intravenous infusion of cyclosporine developed headache, general seizures and cortical blindness. Head magnetic resonance imaging showed spread, cortical-subcortical nonenhancing signal changes. Full neurological recovery was achieved in 24 hours. Cyclosporine was stopped and a single dose of infliximab was infused with rapid improvement of the fistula that at 7 months' follow-up is still closed.
| Original language | English |
|---|---|
| Pages (from-to) | 792-794 |
| Number of pages | 3 |
| Journal | Digestive and Liver Disease |
| Volume | 32 |
| Issue number | 9 |
| Publication status | Published - 2000 |
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Keywords
- Cyclosporine-related neurotoxicity
- Fistulizing Crohn's disease
- Infliximab
ASJC Scopus subject areas
- Gastroenterology
Cite this
A girl with severe fistulizing Crohn's disease. / Barabino, A.; Castellano, E.; Gandullia, P.; Biscaldi, E.
In: Digestive and Liver Disease, Vol. 32, No. 9, 2000, p. 792-794.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A girl with severe fistulizing Crohn's disease
AU - Barabino, A.
AU - Castellano, E.
AU - Gandullia, P.
AU - Biscaldi, E.
PY - 2000
Y1 - 2000
N2 - We report the case of a girl with a severe perianal fistulizing Crohn's disease who during intravenous infusion of cyclosporine developed headache, general seizures and cortical blindness. Head magnetic resonance imaging showed spread, cortical-subcortical nonenhancing signal changes. Full neurological recovery was achieved in 24 hours. Cyclosporine was stopped and a single dose of infliximab was infused with rapid improvement of the fistula that at 7 months' follow-up is still closed.
AB - We report the case of a girl with a severe perianal fistulizing Crohn's disease who during intravenous infusion of cyclosporine developed headache, general seizures and cortical blindness. Head magnetic resonance imaging showed spread, cortical-subcortical nonenhancing signal changes. Full neurological recovery was achieved in 24 hours. Cyclosporine was stopped and a single dose of infliximab was infused with rapid improvement of the fistula that at 7 months' follow-up is still closed.
KW - Cyclosporine-related neurotoxicity
KW - Fistulizing Crohn's disease
KW - Infliximab
UR - http://www.scopus.com/inward/record.url?scp=0034486362&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034486362&partnerID=8YFLogxK
M3 - Article
VL - 32
SP - 792
EP - 794
JO - Digestive and Liver Disease
JF - Digestive and Liver Disease
SN - 1590-8658
IS - 9
ER -