A girl with severe fistulizing Crohn's disease

A. Barabino, E. Castellano, P. Gandullia, E. Biscaldi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We report the case of a girl with a severe perianal fistulizing Crohn's disease who during intravenous infusion of cyclosporine developed headache, general seizures and cortical blindness. Head magnetic resonance imaging showed spread, cortical-subcortical nonenhancing signal changes. Full neurological recovery was achieved in 24 hours. Cyclosporine was stopped and a single dose of infliximab was infused with rapid improvement of the fistula that at 7 months' follow-up is still closed.

Original languageEnglish
Pages (from-to)792-794
Number of pages3
JournalDigestive and Liver Disease
Volume32
Issue number9
Publication statusPublished - 2000

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Crohn Disease
Cyclosporine
Cortical Blindness
Intravenous Infusions
Fistula
Headache
Seizures
Head
Magnetic Resonance Imaging
Infliximab

Keywords

  • Cyclosporine-related neurotoxicity
  • Fistulizing Crohn's disease
  • Infliximab

ASJC Scopus subject areas

  • Gastroenterology

Cite this

A girl with severe fistulizing Crohn's disease. / Barabino, A.; Castellano, E.; Gandullia, P.; Biscaldi, E.

In: Digestive and Liver Disease, Vol. 32, No. 9, 2000, p. 792-794.

Research output: Contribution to journalArticle

Barabino, A, Castellano, E, Gandullia, P & Biscaldi, E 2000, 'A girl with severe fistulizing Crohn's disease', Digestive and Liver Disease, vol. 32, no. 9, pp. 792-794.
Barabino, A. ; Castellano, E. ; Gandullia, P. ; Biscaldi, E. / A girl with severe fistulizing Crohn's disease. In: Digestive and Liver Disease. 2000 ; Vol. 32, No. 9. pp. 792-794.
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