Abstract
We report the case of a girl with a severe perianal fistulizing Crohn's disease who during intravenous infusion of cyclosporine developed headache, general seizures and cortical blindness. Head magnetic resonance imaging showed spread, cortical-subcortical nonenhancing signal changes. Full neurological recovery was achieved in 24 hours. Cyclosporine was stopped and a single dose of infliximab was infused with rapid improvement of the fistula that at 7 months' follow-up is still closed.
Original language | English |
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Pages (from-to) | 792-794 |
Number of pages | 3 |
Journal | Digestive and Liver Disease |
Volume | 32 |
Issue number | 9 |
Publication status | Published - 2000 |
Keywords
- Cyclosporine-related neurotoxicity
- Fistulizing Crohn's disease
- Infliximab
ASJC Scopus subject areas
- Gastroenterology