TY - JOUR
T1 - A Global View to HBV Chronic Infection
T2 - Evolving Strategies for Diagnosis, Treatment and Prevention in Immunocompetent Individuals
AU - Nicolini, Laura Ambra
AU - Orsi, Andrea
AU - Tatarelli, Paola
AU - Viscoli, Claudio
AU - Icardi, Giancarlo
AU - Sticchi, Laura
PY - 2019/9/9
Y1 - 2019/9/9
N2 - Hepatitis B Virus (HBV) is a significant public health challenge. Around 250 million people live with chronic HBV infection. With a global approach to this issue, we focus on new perspective in diagnosis, management and prevention of HBV chronic infection. Precise diagnosis of HBV status is crucial to guide patient management. Although available drugs reduce the risk of liver disease progression, they are not able to definitely eradicate HBV, and new therapeutic options are urgently needed. Thus, prevention of HBV infection is still the most effective strategy to achieve the control of the disease. Key aspects of prevention programs include surveillance of viral hepatitis, screening programs and immunization strategies. In spite of the high success rate of licensed HBV vaccines, a need for improved vaccine persists, especially in order to provide coverage of current non-responders.
AB - Hepatitis B Virus (HBV) is a significant public health challenge. Around 250 million people live with chronic HBV infection. With a global approach to this issue, we focus on new perspective in diagnosis, management and prevention of HBV chronic infection. Precise diagnosis of HBV status is crucial to guide patient management. Although available drugs reduce the risk of liver disease progression, they are not able to definitely eradicate HBV, and new therapeutic options are urgently needed. Thus, prevention of HBV infection is still the most effective strategy to achieve the control of the disease. Key aspects of prevention programs include surveillance of viral hepatitis, screening programs and immunization strategies. In spite of the high success rate of licensed HBV vaccines, a need for improved vaccine persists, especially in order to provide coverage of current non-responders.
KW - HBV chronic infection
KW - HBV diagnosis
KW - HBV prevention
KW - HBV treatment
KW - HBV vaccine
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U2 - 10.3390/ijerph16183307
DO - 10.3390/ijerph16183307
M3 - Article
C2 - 31505743
AN - SCOPUS:85072022137
VL - 16
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
SN - 1661-7827
IS - 18
M1 - 3307
ER -