A growth factor different from IL-6 promotes the growth of Epstein-Barr virus-transformed cells at low cell density

Claudia Negri, Antonella Cerino, Roberto Chiesa e, Giulia C B Astaldi Ricotti

Research output: Contribution to journalArticlepeer-review

Abstract

Interleukin-6 (IL-6) was recently described to support the growth of Epstein-Barr (EBV) transformed lymphocytes. However no effect was reported on cloning of EBV transformed lymphocytes under limiting dilution conditions. In this paper we demonstrate that the Supernatant of Human Endothelial Cells (HECS) contains a factor(s) different from IL-6 which induces high cloning efficiency of EBV transformed cell lines, cultured under limiting dilution conditions. Furthermore HECS is superior to IL-6 in all the passages of EBV lymphocytes transformation.

Original languageEnglish
Pages (from-to)132-133
Number of pages2
JournalCytotechnology
Volume5
Issue number1 Supplement
DOIs
Publication statusPublished - Feb 1991

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology
  • Biotechnology

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