A high-resolution genetic map of mouse Chromosome 15 encompassing the Dominant megacolon (Dom) locus

A. Puliti, M. O. Prehu, D. Simon-Chazottes, L. Ferkdadji, M. Peuchmaur, M. Goossens, J. L. Guénet

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Dominant megacolon (Dom) is one of four mutations in the mouse that can produce a phenotype similar to Hirschsprung disease in human. The Dom gene product is not known, and no candidate region has been defined for a possible human homolog. In this publication we report mapping the Dom locus with high definition, using several intra- and interspecific crosses and a set of 16 Chr 15-specific microsatellites flanking this locus.

Original languageEnglish
Pages (from-to)763-768
Number of pages6
JournalMammalian Genome
Volume6
Issue number11
DOIs
Publication statusPublished - Nov 1995

Fingerprint

Megacolon
Chromosomes, Human, Pair 15
Dominant Genes
Hirschsprung Disease
Microsatellite Repeats
Phenotype
Mutation

ASJC Scopus subject areas

  • Genetics

Cite this

Puliti, A., Prehu, M. O., Simon-Chazottes, D., Ferkdadji, L., Peuchmaur, M., Goossens, M., & Guénet, J. L. (1995). A high-resolution genetic map of mouse Chromosome 15 encompassing the Dominant megacolon (Dom) locus. Mammalian Genome, 6(11), 763-768. https://doi.org/10.1007/BF00539000

A high-resolution genetic map of mouse Chromosome 15 encompassing the Dominant megacolon (Dom) locus. / Puliti, A.; Prehu, M. O.; Simon-Chazottes, D.; Ferkdadji, L.; Peuchmaur, M.; Goossens, M.; Guénet, J. L.

In: Mammalian Genome, Vol. 6, No. 11, 11.1995, p. 763-768.

Research output: Contribution to journalArticle

Puliti, A, Prehu, MO, Simon-Chazottes, D, Ferkdadji, L, Peuchmaur, M, Goossens, M & Guénet, JL 1995, 'A high-resolution genetic map of mouse Chromosome 15 encompassing the Dominant megacolon (Dom) locus', Mammalian Genome, vol. 6, no. 11, pp. 763-768. https://doi.org/10.1007/BF00539000
Puliti, A. ; Prehu, M. O. ; Simon-Chazottes, D. ; Ferkdadji, L. ; Peuchmaur, M. ; Goossens, M. ; Guénet, J. L. / A high-resolution genetic map of mouse Chromosome 15 encompassing the Dominant megacolon (Dom) locus. In: Mammalian Genome. 1995 ; Vol. 6, No. 11. pp. 763-768.
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