TY - JOUR
T1 - A historical cohort mortality study among shipyard workers in Genoa, Italy
AU - Puntoni, Riccardo
AU - Merlo, Franco
AU - Borsa, Luca
AU - Reggiardo, Giorgio
AU - Garrone, Elsa
AU - Ceppi, Marcello
PY - 2001
Y1 - 2001
N2 - Background: A historical cohort mortality study was conducted among 3984 shipyard workers assigned to ship repair, refitting, and construction in the harbor of Genoa, Italy, between 1960 and 1981. These workers were exposed to asbestos fibers, welding fumes and gases, silica dust, polycyclic aromatic hydrocarbons, and solvents. Methods: Workers were classified in 20 different job-titles depending upon the type of activity. Standardized mortality ratios (SMRs) were computed using male residents of the Province of Genoa as the referent population. Results and Conclusions: For the whole cohort significantly increased SMRs were detected for all causes, all cancers, liver, larynx, lung, pleural and bladder cancers, respiratory tract diseases, and cirrhosis of the liver. The analysis by job-title showed increased SMRs not only for pleural cancer, but also for lung, laryngeal cancers and respiratory tract diseases in occupations entailing heavy asbestos exposure. Bladder and liver cancers and liver cirrhosis mortality also appeared to be related to occupational exposure.
AB - Background: A historical cohort mortality study was conducted among 3984 shipyard workers assigned to ship repair, refitting, and construction in the harbor of Genoa, Italy, between 1960 and 1981. These workers were exposed to asbestos fibers, welding fumes and gases, silica dust, polycyclic aromatic hydrocarbons, and solvents. Methods: Workers were classified in 20 different job-titles depending upon the type of activity. Standardized mortality ratios (SMRs) were computed using male residents of the Province of Genoa as the referent population. Results and Conclusions: For the whole cohort significantly increased SMRs were detected for all causes, all cancers, liver, larynx, lung, pleural and bladder cancers, respiratory tract diseases, and cirrhosis of the liver. The analysis by job-title showed increased SMRs not only for pleural cancer, but also for lung, laryngeal cancers and respiratory tract diseases in occupations entailing heavy asbestos exposure. Bladder and liver cancers and liver cirrhosis mortality also appeared to be related to occupational exposure.
KW - Asbestos
KW - Cohort study
KW - Lung cancer
KW - Mesothelioma
KW - Occupational cancers
KW - Shipyard
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U2 - 10.1002/ajim.1110
DO - 10.1002/ajim.1110
M3 - Article
C2 - 11598985
AN - SCOPUS:0034817293
VL - 40
SP - 363
EP - 370
JO - American Journal of Industrial Medicine
JF - American Journal of Industrial Medicine
SN - 0271-3586
IS - 4
ER -