A human short-chain dehydrogenase/reductase gene: Structure, chromosomal localization, tissue expression and subcellular localization of its product

Silvia Pellegrini; Stefano Censini; Silvia Guidotti; Paola Iacopetti; Mariano Rocchi; Marco Bianchi; Antonello Covacci; Franco Gabrielli

doi:10.1016/S0167-4781(01)00323-2

A human short-chain dehydrogenase/reductase gene: Structure, chromosomal localization, tissue expression and subcellular localization of its product

Silvia Pellegrini, Stefano Censini, Silvia Guidotti, Paola Iacopetti, Mariano Rocchi, Marco Bianchi, Antonello Covacci, Franco Gabrielli

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

We have previously described the cloning of Hep27, a short-chain dehydrogenase/reductase, which is synthesized in human hepatoblastoma HepG2 cells following growth arrest induced by butyrate treatment. The present report describes the cloning, the structure and the physical and cytogenetic mapping of the gene coding for Hep27. We also show that Hep27 is synthesized in a limited number of human normal tissues and that it is localized in the nuclei and cytoplasm of HepG2 cells.

Original language	English
Pages (from-to)	215-222
Number of pages	8
Journal	BBA - Gene Structure and Expression
Volume	1574
Issue number	3
DOIs	https://doi.org/10.1016/S0167-4781(01)00323-2
Publication status	Published - Apr 12 2002

Keywords

Chromosome 14
Gene
Gene expression
Human
Short chain dehydrogenase/reductase

ASJC Scopus subject areas

Biochemistry
Biophysics
Genetics
Structural Biology

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10.1016/S0167-4781(01)00323-2

Cite this

Pellegrini, S., Censini, S., Guidotti, S., Iacopetti, P., Rocchi, M., Bianchi, M., Covacci, A., & Gabrielli, F. (2002). A human short-chain dehydrogenase/reductase gene: Structure, chromosomal localization, tissue expression and subcellular localization of its product. BBA - Gene Structure and Expression, 1574(3), 215-222. https://doi.org/10.1016/S0167-4781(01)00323-2

A human short-chain dehydrogenase/reductase gene : Structure, chromosomal localization, tissue expression and subcellular localization of its product. / Pellegrini, Silvia; Censini, Stefano; Guidotti, Silvia; Iacopetti, Paola; Rocchi, Mariano; Bianchi, Marco; Covacci, Antonello; Gabrielli, Franco.

In: BBA - Gene Structure and Expression, Vol. 1574, No. 3, 12.04.2002, p. 215-222.

Research output: Contribution to journal › Article › peer-review

Pellegrini, S, Censini, S, Guidotti, S, Iacopetti, P, Rocchi, M, Bianchi, M, Covacci, A & Gabrielli, F 2002, 'A human short-chain dehydrogenase/reductase gene: Structure, chromosomal localization, tissue expression and subcellular localization of its product', BBA - Gene Structure and Expression, vol. 1574, no. 3, pp. 215-222. https://doi.org/10.1016/S0167-4781(01)00323-2

Pellegrini, Silvia ; Censini, Stefano ; Guidotti, Silvia ; Iacopetti, Paola ; Rocchi, Mariano ; Bianchi, Marco ; Covacci, Antonello ; Gabrielli, Franco. / A human short-chain dehydrogenase/reductase gene : Structure, chromosomal localization, tissue expression and subcellular localization of its product. In: BBA - Gene Structure and Expression. 2002 ; Vol. 1574, No. 3. pp. 215-222.

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AU - Covacci, Antonello

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A human short-chain dehydrogenase/reductase gene: Structure, chromosomal localization, tissue expression and subcellular localization of its product

Abstract

Keywords

ASJC Scopus subject areas

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