Abstract
In subjects affected by chronic periodontitis, the chemical control of plaque is a strategy aiming primarily at controlling infection and bacterial loading. The aim is to evaluate the bacterial loading of the so-called 'red complex' associated with a short-term use of a hydrosilver gel (HSG) by using an in vivo model in adult subjects affected by chronic periodontitis. This prospective short-term clinical trial involved 10 adult volunteers using a 15-day in vivo model. After receiving professional prophylaxis at baseline (t0), each volunteer performed daily applications of HSG at home. After 15 days (t1) from the first application, subgingival plaque samples were collected, and the bacterial loading of species belonging to the red complex was evaluated using polymerase chain reaction (PCR) analyses. The bacterial loading of the red complex showed no statistically significant difference between t0 and t1, although it tended to decrease. HSG can be used at home as an adjunct to domestic oral care because it seems a promising tool, but further studies are needed to involve a larger sample and a longer follow-up.
| Original language | English |
|---|---|
| Pages (from-to) | 2058738418825212 |
| Journal | International Journal of Immunopathology and Pharmacology |
| Volume | 33 |
| DOIs | |
| Publication status | Published - Jan 1 2019 |
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Keywords
- bacterial loading
- chronic periodontitis
- domestic oral hygiene
- hydrosilver gel
- red complex
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Pharmacology
Cite this
A hydrosilver gel for plaque control in adults affected by chronic periodontitis : Effects on the 'red complex' bacterial load. A prospective longitudinal pilot study using polymerase chain reaction analysis. / Lauritano, Dorina; Nota, Alessandro; Martinelli, Marcella; Severino, Marco; Romano, Michele; Rossi, Diego; Caruso, Silvia.
In: International Journal of Immunopathology and Pharmacology, Vol. 33, 01.01.2019, p. 2058738418825212.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A hydrosilver gel for plaque control in adults affected by chronic periodontitis
T2 - Effects on the 'red complex' bacterial load. A prospective longitudinal pilot study using polymerase chain reaction analysis
AU - Lauritano, Dorina
AU - Nota, Alessandro
AU - Martinelli, Marcella
AU - Severino, Marco
AU - Romano, Michele
AU - Rossi, Diego
AU - Caruso, Silvia
PY - 2019/1/1
Y1 - 2019/1/1
N2 - In subjects affected by chronic periodontitis, the chemical control of plaque is a strategy aiming primarily at controlling infection and bacterial loading. The aim is to evaluate the bacterial loading of the so-called 'red complex' associated with a short-term use of a hydrosilver gel (HSG) by using an in vivo model in adult subjects affected by chronic periodontitis. This prospective short-term clinical trial involved 10 adult volunteers using a 15-day in vivo model. After receiving professional prophylaxis at baseline (t0), each volunteer performed daily applications of HSG at home. After 15 days (t1) from the first application, subgingival plaque samples were collected, and the bacterial loading of species belonging to the red complex was evaluated using polymerase chain reaction (PCR) analyses. The bacterial loading of the red complex showed no statistically significant difference between t0 and t1, although it tended to decrease. HSG can be used at home as an adjunct to domestic oral care because it seems a promising tool, but further studies are needed to involve a larger sample and a longer follow-up.
AB - In subjects affected by chronic periodontitis, the chemical control of plaque is a strategy aiming primarily at controlling infection and bacterial loading. The aim is to evaluate the bacterial loading of the so-called 'red complex' associated with a short-term use of a hydrosilver gel (HSG) by using an in vivo model in adult subjects affected by chronic periodontitis. This prospective short-term clinical trial involved 10 adult volunteers using a 15-day in vivo model. After receiving professional prophylaxis at baseline (t0), each volunteer performed daily applications of HSG at home. After 15 days (t1) from the first application, subgingival plaque samples were collected, and the bacterial loading of species belonging to the red complex was evaluated using polymerase chain reaction (PCR) analyses. The bacterial loading of the red complex showed no statistically significant difference between t0 and t1, although it tended to decrease. HSG can be used at home as an adjunct to domestic oral care because it seems a promising tool, but further studies are needed to involve a larger sample and a longer follow-up.
KW - bacterial loading
KW - chronic periodontitis
KW - domestic oral hygiene
KW - hydrosilver gel
KW - red complex
UR - http://www.scopus.com/inward/record.url?scp=85074301902&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85074301902&partnerID=8YFLogxK
U2 - 10.1177/2058738418825212
DO - 10.1177/2058738418825212
M3 - Article
C2 - 31663441
AN - SCOPUS:85074301902
VL - 33
SP - 2058738418825212
JO - International Journal of Immunopathology and Pharmacology
JF - International Journal of Immunopathology and Pharmacology
SN - 0394-6320
ER -