A magnetic resonance imaging study of the cervical cord of patients with CADASIL

M. A. Rocca, Massimo Filippi, J. Herzog, M. P. Sormani, M. Dichgans, T. A. Yousry

Research output: Contribution to journalArticlepeer-review

Abstract

The authors obtained MR and magnetization transfer (MT) imaging of the cervical cord from 25 patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). They found no conventional MR abnormalities, but a reduced peak height of the MT ratio (MTR) histogram. This suggests a reduced amount of "truly" normal cord tissue in CADASIL. A significant correlation was found between the extent of brain lesions and cord MTR, suggesting wallerian degeneration as the substrate of the cord MTR changes.

Original languageEnglish
Pages (from-to)1392-1394
Number of pages3
JournalNeurology
Volume56
Issue number10
Publication statusPublished - May 22 2001

ASJC Scopus subject areas

  • Neuroscience(all)

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