A matched pair analysis of multicenter longterm follow-up after split-liver transplantation with extended right grafts

Michael W Ross, Matteo Cescon, Roberta Angelico, Enzo Andorno, Giorgio Rossi, Antonio Pinna, Luciano De Carlis, Umberto Baccarani, Umberto Cillo, Michele Colledan, Vincenzo Mazzaferro, Giuseppe Tisone, Massimo Rossi, Fabio Tuzzolino, Duilio Pagano, Salvatore Gruttadauria, George Mazariegos, Bruno Gridelli, Marco Spada

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Abstract

Split-liver transplantation has been proposed as an alternative to whole liver (WL) transplantation to expand the donor pool, but studies comparing adult longterm outcomes between the 2 methods are conflicting and limited. This is the first Italian multicenter study that retrospectively analyzed 119 matched-pair recipients of whole and extended right grafts (ERGs) for longterm survival outcomes. In the overall population, WL recipients showed higher patient survival at 1 (93% versus 73%), 5 (87% versus 65%), and 10 years (83% versus 60%) after transplantation compared with split-liver recipients (P 50, donor-to-recipient weight ratio 
Original languageEnglish
Pages (from-to)1384-1395
Number of pages12
JournalLiver Transplantation
Volume23
Issue number11
DOIs
Publication statusPublished - Nov 2017

Keywords

  • Journal Article

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    Ross, M. W., Cescon, M., Angelico, R., Andorno, E., Rossi, G., Pinna, A., De Carlis, L., Baccarani, U., Cillo, U., Colledan, M., Mazzaferro, V., Tisone, G., Rossi, M., Tuzzolino, F., Pagano, D., Gruttadauria, S., Mazariegos, G., Gridelli, B., & Spada, M. (2017). A matched pair analysis of multicenter longterm follow-up after split-liver transplantation with extended right grafts. Liver Transplantation, 23(11), 1384-1395. https://doi.org/10.1002/lt.24808