We propose a model for the dynamics of the immune system by considering the subpopulations of virgin and memory T lymphocytes on a time scale corresponding to the human life span. In the deterministic balance equation we introduce a fluctuating term in order to take into account the chronic antigenic stress. Starting from the hypothesis that the depletion of virgin cells with cytotoxicproperties (CD8+) is a mortality marker, the model provides survival curves quite similar to the demographic curves.
|Number of pages||14|
|Journal||Rivista di Biologia - Biology Forum|
|Publication status||Published - May 2001|
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)