A method to determine the margin of safety for microneedles arrays

E. Forvi, M. Soncini, M. Bedoni, F. Rizzo, M. Casella, C. O'Mahony, F. Gramatica

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Microneedles, before being used for biomedical applications, have to satisfy biological and technical specifications, in particular they must guarantee a sufficient strength during exercise. Although studies on the mechanical characterization on single microneedles are reported in literature, microneedles must be arranged in matrices to be used in real biomedical applications. For these reasons, it is necessary to define a margin of safety for complete arrays of microneedles. In this study forces required to pierce human skin, by means of piercing tests, and maximum forces which arrays can withstand without breaking, through compressive tests, are carried out to determine a preliminary margin of safety for microneedles arrays.

Original languageEnglish
Title of host publicationWCE 2010 - World Congress on Engineering 2010
Pages1550-1554
Number of pages5
Volume2
Publication statusPublished - 2010
EventWorld Congress on Engineering 2010, WCE 2010 - London, United Kingdom
Duration: Jun 30 2010Jul 2 2010

Other

OtherWorld Congress on Engineering 2010, WCE 2010
CountryUnited Kingdom
CityLondon
Period6/30/107/2/10

    Fingerprint

Keywords

  • Array
  • Mechanical characterization
  • Microneedles

ASJC Scopus subject areas

  • Computer Science(all)
  • Engineering(all)

Cite this

Forvi, E., Soncini, M., Bedoni, M., Rizzo, F., Casella, M., O'Mahony, C., & Gramatica, F. (2010). A method to determine the margin of safety for microneedles arrays. In WCE 2010 - World Congress on Engineering 2010 (Vol. 2, pp. 1550-1554)