A microbiological and morphological study of blocked biliary stents

Roberta Di Rosa, Antonio Basoli, Gianfranco Donelli, Adrio Penni, Filippo Maria Salvatori, Fausto Fiocca, Lucilla Baldassarri

Research output: Contribution to journalArticlepeer-review

Abstract

Biliary stent blockade represents the main limitation of the use of such devices in relieving obstructive jaundice due to a variety of malignant and benign conditions. Microbiological and morphological analysis of the occluding sludge present on the inner surface of 30 biliary stents was performed to evaluate the different components of such material and the effect of the antibiotic treatment on the biofilm formation. A highly organized biofilm, constituted by microbial cells embedded in an amorphous matrix together with crystallized bile salts, was observed Enterococcus spp. represented the most common isolate from both occluded and non-occluded stents. The antibiotic therapy, while selecting for multi-resistant bacteria and fungi, might possibly delay the biofilm formation.

Original languageEnglish
Pages (from-to)84-88
Number of pages5
JournalMicrobial Ecology in Health and Disease
Volume11
Issue number2
DOIs
Publication statusPublished - Mar 1999

Keywords

  • Biliary stents
  • Biofilm
  • Microbial colonization

ASJC Scopus subject areas

  • Ecology
  • Microbiology

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