A “minimalistic hybrid algorithm” in coronary chronic total occlusion revascularization: Procedural and clinical outcomes

Carlo Zivelonghi, Jan Peter van Kuijk, Enrico Poletti, Maarten J. Suttorp, Frank D. Eefting, Benno J. Rensing, Jurrien M. ten Berg, Antonio Colombo, Lorenzo Azzalini, Pierfrancesco Agostoni

Research output: Contribution to journalArticlepeer-review


Background: Percutaneous recanalization of coronary chronic total occlusions (CTOs) traditionally relies on the use of dual-access and large bore catheters, with trans-femoral approach adoption in most cases. Objectives: Aim of this manuscript is to describe the outcomes of an alternative hybrid algorithm, called “Minimalistic Hybrid Algorithm,” which has the purpose to minimize the use of double access, large bore catheters, and femoral approach in order to minimize the risk of vascular complications and patient's discomfort, without compromising efficacy. Methods: In this single-center registry, a “minimalistic” approach was attempted in consecutive patients undergoing CTO PCI between March 2016 and October 2017. Data regarding the applicability of this algorithm and the related procedural success rates were collected, together with common demographic and angiographic characteristics. Results: Of the 100 CTO PCI performed in the study period, 91(91%) were successfully approached according to the novel algorithm. Mean J-CTO score of all minimalistic procedures was 1.9 ± 1.2, with 31(34%) patients presenting with J-CTO score ≥3. In 52 procedures, the approach consisted of single-catheter access, 49(94.2%) of which were trans-radial. Out of the 39 patients approached with dual-catheters, 26(69.2%) were biradial, and 8(21%) radial-femoral. Procedural success in patients approached with the minimalistic algorithm was 89%, in line with the results of large-multicenter experiences nowadays available. Conclusions: Our results show that an alternative algorithm limiting the routine use of large bore catheters and trans-femoral approach is feasible in the clinical practice and yields good procedural outcomes.

Original languageEnglish
Pages (from-to)97-104
Number of pages8
JournalCatheterization and Cardiovascular Interventions
Issue number1
Publication statusPublished - Jan 1 2020


  • chronic total occlusion
  • hybrid algorithm
  • radial access

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'A “minimalistic hybrid algorithm” in coronary chronic total occlusion revascularization: Procedural and clinical outcomes'. Together they form a unique fingerprint.

Cite this