Abstract
A multitude of therapies is available to treat disc herniation, ranging from conservative methods (medication and physical therapy) to minimally invasive (percutaneous) treatments and surgery. O 2-O 3 chemonucleolysis (O 2-O 3 therapy) is one of the minimally invasive treatments with the best cost/benefit ratio and lowest complication rate. Another substance recently made available exploiting the chemical properties of pure ethanol is DiscoGel®, a radiopaque gelified ethanol more viscous than absolute alcohol 8,9. The present study aimed to assess the therapeutic outcome of DiscoGel® chemonucleolysis in patients with lumbar disc herniation unresponsive to O 2-O 3 therapy. Thirty-two patients aged between 20 and 79 years were treated by DiscoGel® chemonucleolysis between December 2008 and January 2010. The treatment was successful (improvement in pain) in 24 out of 32 patients. DiscoGel® is safe and easy to handle and there were no complications related to product diffusivity outside the treatment site. The therapeutic success rate of DiscoGel® chemonucleolysis in patients unresponsive to O 2-O 3 therapy was satisfactory. Among other methods used to treat lumbar disc herniation, DiscoGel® chemonucleolysis can be deemed an intermediate procedure bridging conservative medical treatments and surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 97-104 |
| Number of pages | 8 |
| Journal | Interventional Neuroradiology |
| Volume | 18 |
| Issue number | 1 |
| Publication status | Published - Mar 2012 |
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Keywords
- Discal hernia
- DiscoGel
- Ozone
- Percutaneous treatments
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology
- Cardiology and Cardiovascular Medicine
Cite this
A minimally invasive treatment for lumbar disc herniation : DiscoGel® chemonucleolysis in patients unresponsive to chemonucleolysis with oxygen-ozone. / Stagni, S.; De Santis, F.; Cirillo, L.; Dall'Olio, M.; Princiotta, C.; Simonetti, L.; Stafa, A.; Leonardi, Marco.
In: Interventional Neuroradiology, Vol. 18, No. 1, 03.2012, p. 97-104.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A minimally invasive treatment for lumbar disc herniation
T2 - DiscoGel® chemonucleolysis in patients unresponsive to chemonucleolysis with oxygen-ozone
AU - Stagni, S.
AU - De Santis, F.
AU - Cirillo, L.
AU - Dall'Olio, M.
AU - Princiotta, C.
AU - Simonetti, L.
AU - Stafa, A.
AU - Leonardi, Marco
PY - 2012/3
Y1 - 2012/3
N2 - A multitude of therapies is available to treat disc herniation, ranging from conservative methods (medication and physical therapy) to minimally invasive (percutaneous) treatments and surgery. O 2-O 3 chemonucleolysis (O 2-O 3 therapy) is one of the minimally invasive treatments with the best cost/benefit ratio and lowest complication rate. Another substance recently made available exploiting the chemical properties of pure ethanol is DiscoGel®, a radiopaque gelified ethanol more viscous than absolute alcohol 8,9. The present study aimed to assess the therapeutic outcome of DiscoGel® chemonucleolysis in patients with lumbar disc herniation unresponsive to O 2-O 3 therapy. Thirty-two patients aged between 20 and 79 years were treated by DiscoGel® chemonucleolysis between December 2008 and January 2010. The treatment was successful (improvement in pain) in 24 out of 32 patients. DiscoGel® is safe and easy to handle and there were no complications related to product diffusivity outside the treatment site. The therapeutic success rate of DiscoGel® chemonucleolysis in patients unresponsive to O 2-O 3 therapy was satisfactory. Among other methods used to treat lumbar disc herniation, DiscoGel® chemonucleolysis can be deemed an intermediate procedure bridging conservative medical treatments and surgery.
AB - A multitude of therapies is available to treat disc herniation, ranging from conservative methods (medication and physical therapy) to minimally invasive (percutaneous) treatments and surgery. O 2-O 3 chemonucleolysis (O 2-O 3 therapy) is one of the minimally invasive treatments with the best cost/benefit ratio and lowest complication rate. Another substance recently made available exploiting the chemical properties of pure ethanol is DiscoGel®, a radiopaque gelified ethanol more viscous than absolute alcohol 8,9. The present study aimed to assess the therapeutic outcome of DiscoGel® chemonucleolysis in patients with lumbar disc herniation unresponsive to O 2-O 3 therapy. Thirty-two patients aged between 20 and 79 years were treated by DiscoGel® chemonucleolysis between December 2008 and January 2010. The treatment was successful (improvement in pain) in 24 out of 32 patients. DiscoGel® is safe and easy to handle and there were no complications related to product diffusivity outside the treatment site. The therapeutic success rate of DiscoGel® chemonucleolysis in patients unresponsive to O 2-O 3 therapy was satisfactory. Among other methods used to treat lumbar disc herniation, DiscoGel® chemonucleolysis can be deemed an intermediate procedure bridging conservative medical treatments and surgery.
KW - Discal hernia
KW - DiscoGel
KW - Ozone
KW - Percutaneous treatments
UR - http://www.scopus.com/inward/record.url?scp=84859973878&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859973878&partnerID=8YFLogxK
M3 - Article
C2 - 22440607
AN - SCOPUS:84859973878
VL - 18
SP - 97
EP - 104
JO - Interventional Neuroradiology
JF - Interventional Neuroradiology
SN - 1591-0199
IS - 1
ER -