A Mobile Application for Exercise Intervention in People Living with HIV

Matteo Bonato, Filippo Turrini, Valentina DE Zan, Andrea Meloni, Marta Plebani, Elena Brambilla, Alessandra Giordani, Chiara Vitobello, Roberta Caccia, Maria Francesca Piacentini, Antonio LA Torre, Adriano Lazzarin, Giampiero Merati, Laura Galli, Paola Cinque

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: To assess 16-weeks improvements of physical fitness, metabolic and psychologic parameters in people living with HIV (PLWH) exercising with the support of a smartphone application, as compared to a control group exercising without application.

METHODS: This was a randomized, open-label, pilot study enrolling PLWH in a 16-week protocol consisting of moderate physical activity three times/week, which included an initial coach-supervised period of 4 weeks, followed by 12 weeks where participants trained independently. Participants were allocated to either an experimental group that trained with the use of a smartphone application (APP) or a control group that practiced following a hard copy training program (No-APP). At baseline (BL) and after 16-weeks (W16), patients were assessed for cardiorespiratory fitness, body composition, blood lipid profile, and profile of mood states (POMS).

RESULTS: Forty-eight PLWH were screened and 38 were eligible: 20 were allocated to the APP group and 18 to the No-APP group. Two APP and two No-APP participants were lost to follow-up. Intention-to-treat analysis showed a W16 improvement from BL of ≥15% V[Combining Dot Above]O2peak in 13 of 18 (72%) in APP, but only in 3 of 16 (19%) in No-APP participants (p=0.025). Significant W16 improvements were observed in APP, but not in No-APP participants, in V[Combining Dot Above]O2peak, fat mass and fat-free mass %, total-, LDL-cholesterol and triglycerides, vigour and total mood by POMS. Accordingly, significant % change differences between the APP and the No-APP groups were observed in V[Combining Dot Above]O2peak, fat and fat-free mass %, total-, LDL-cholesterol and triglycerides, and in depression, vigour, anger and total mood by POMS.

CONCLUSIONS: Exercising with the use of a smartphone application improved cardiorespiratory fitness, body composition, cholesterol profiles and psychological outcomes in PLWH.

Original languageEnglish
Pages (from-to)425-433
Number of pages9
JournalMedicine and Science in Sports and Exercise
Volume52
Issue number2
DOIs
Publication statusPublished - Feb 2020

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