A model for fatigue generation and exercise prescription in multiple sclerosis patients

Luigi Tesio; L. Perucca; A. Bellafà

doi:10.1007/s10072-006-0645-4

A model for fatigue generation and exercise prescription in multiple sclerosis patients

Luigi Tesio, L. Perucca, A. Bellafà

Fondazione Istituto Auxologico Italiano

Research output: Contribution to journal › Article › peer-review

Abstract

Persons with multiple sclerosis often suffer from fatigue primarily reflecting the burden of disease. The most direct manifestation is an increased sense of effort for even light activities. This can be thought of as the result of "inefficiency" in the neural programme that translates the motor intention into the proper pattern of muscle contractions. A model is proposed, based on the mismatch between the actual movement and the "efference copy" of the motor programme. Examples of exercises consistent with this model are provided.

Original language	English
Journal	Neurological Sciences
Volume	27
Issue number	SUPPL. 4
DOIs	https://doi.org/10.1007/s10072-006-0645-4
Publication status	Published - Sep 2006

Keywords

Effort
Exercise
Fatigue
Multiple sclerosis
Rehabilitation

ASJC Scopus subject areas

Clinical Neurology
Neuroscience(all)

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10.1007/s10072-006-0645-4

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AB - Persons with multiple sclerosis often suffer from fatigue primarily reflecting the burden of disease. The most direct manifestation is an increased sense of effort for even light activities. This can be thought of as the result of "inefficiency" in the neural programme that translates the motor intention into the proper pattern of muscle contractions. A model is proposed, based on the mismatch between the actual movement and the "efference copy" of the motor programme. Examples of exercises consistent with this model are provided.

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A model for fatigue generation and exercise prescription in multiple sclerosis patients

Abstract

Keywords

ASJC Scopus subject areas

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