A molecular thermometer for nanoparticles for optical hyperthermia

Stefano Freddi; Laura Sironi; Rocco D'Antuono; Diego Morone; Alice Donà; Elisa Cabrini; Laura D'Alfonso; Maddalena Collini; Piersandro Pallavicini; Giovanni Baldi; Daniela Maggioni; Giuseppe Chirico

doi:10.1021/nl400129v

A molecular thermometer for nanoparticles for optical hyperthermia

Stefano Freddi, Laura Sironi, Rocco D'Antuono, Diego Morone, Alice Donà, Elisa Cabrini, Laura D'Alfonso, Maddalena Collini, Piersandro Pallavicini, Giovanni Baldi, Daniela Maggioni, Giuseppe Chirico

Istituto Clinico Humanitas

Research output: Contribution to journal › Article › peer-review

Abstract

We developed an all-optical method to measure the temperature on gold (nanorods and nanostars) and magnetite nanoparticles under near-infrared and radiofrequency excitation by monitoring the excited state lifetime of Rhodamine B that lies within ≅20 nm from the nanoparticle surface. We reached high temperature sensitivity (0.029 ± 0.001 ns/ C) and low uncertainty (±0.3 C). Gold nanostars are ≅3 and ≅100 times more efficient than gold nanorods and magnetite nanoparticles in inducing localized hyperthermia.

Original language	English
Pages (from-to)	2004-2010
Number of pages	7
Journal	Nano Letters
Volume	13
Issue number	5
DOIs	https://doi.org/10.1021/nl400129v
Publication status	Published - May 8 2013

Keywords

Fluorescence
gold nanoparticles
hyperthermia
near-infrared
thermology

ASJC Scopus subject areas

Condensed Matter Physics
Bioengineering
Chemistry(all)
Materials Science(all)
Mechanical Engineering
Medicine(all)

Access to Document

10.1021/nl400129v

Cite this

A molecular thermometer for nanoparticles for optical hyperthermia. / Freddi, Stefano; Sironi, Laura; D'Antuono, Rocco; Morone, Diego; Donà, Alice; Cabrini, Elisa; D'Alfonso, Laura; Collini, Maddalena; Pallavicini, Piersandro; Baldi, Giovanni; Maggioni, Daniela; Chirico, Giuseppe.

In: Nano Letters, Vol. 13, No. 5, 08.05.2013, p. 2004-2010.

Research output: Contribution to journal › Article › peer-review

@article{7a486b294eb7414ca979a5f017d7bb9e,

title = "A molecular thermometer for nanoparticles for optical hyperthermia",

abstract = "We developed an all-optical method to measure the temperature on gold (nanorods and nanostars) and magnetite nanoparticles under near-infrared and radiofrequency excitation by monitoring the excited state lifetime of Rhodamine B that lies within ≅20 nm from the nanoparticle surface. We reached high temperature sensitivity (0.029 ± 0.001 ns/ C) and low uncertainty (±0.3 C). Gold nanostars are ≅3 and ≅100 times more efficient than gold nanorods and magnetite nanoparticles in inducing localized hyperthermia.",

keywords = "Fluorescence, gold nanoparticles, hyperthermia, near-infrared, thermology",

author = "Stefano Freddi and Laura Sironi and Rocco D'Antuono and Diego Morone and Alice Don{\`a} and Elisa Cabrini and Laura D'Alfonso and Maddalena Collini and Piersandro Pallavicini and Giovanni Baldi and Daniela Maggioni and Giuseppe Chirico",

year = "2013",

month = may,

day = "8",

doi = "10.1021/nl400129v",

language = "English",

volume = "13",

pages = "2004--2010",

journal = "Nano Letters",

issn = "1530-6984",

publisher = "American Chemical Society",

number = "5",

}

TY - JOUR

T1 - A molecular thermometer for nanoparticles for optical hyperthermia

AU - Freddi, Stefano

AU - Sironi, Laura

AU - D'Antuono, Rocco

AU - Morone, Diego

AU - Donà, Alice

AU - Cabrini, Elisa

AU - D'Alfonso, Laura

AU - Collini, Maddalena

AU - Pallavicini, Piersandro

AU - Baldi, Giovanni

AU - Maggioni, Daniela

AU - Chirico, Giuseppe

PY - 2013/5/8

Y1 - 2013/5/8

N2 - We developed an all-optical method to measure the temperature on gold (nanorods and nanostars) and magnetite nanoparticles under near-infrared and radiofrequency excitation by monitoring the excited state lifetime of Rhodamine B that lies within ≅20 nm from the nanoparticle surface. We reached high temperature sensitivity (0.029 ± 0.001 ns/ C) and low uncertainty (±0.3 C). Gold nanostars are ≅3 and ≅100 times more efficient than gold nanorods and magnetite nanoparticles in inducing localized hyperthermia.

AB - We developed an all-optical method to measure the temperature on gold (nanorods and nanostars) and magnetite nanoparticles under near-infrared and radiofrequency excitation by monitoring the excited state lifetime of Rhodamine B that lies within ≅20 nm from the nanoparticle surface. We reached high temperature sensitivity (0.029 ± 0.001 ns/ C) and low uncertainty (±0.3 C). Gold nanostars are ≅3 and ≅100 times more efficient than gold nanorods and magnetite nanoparticles in inducing localized hyperthermia.

KW - Fluorescence

KW - gold nanoparticles

KW - hyperthermia

KW - near-infrared

KW - thermology

UR - http://www.scopus.com/inward/record.url?scp=84877309041&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84877309041&partnerID=8YFLogxK

U2 - 10.1021/nl400129v

DO - 10.1021/nl400129v

M3 - Article

C2 - 23611425

AN - SCOPUS:84877309041

VL - 13

SP - 2004

EP - 2010

JO - Nano Letters

JF - Nano Letters

SN - 1530-6984

IS - 5

ER -

A molecular thermometer for nanoparticles for optical hyperthermia

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this