A molecular thermometer for nanoparticles for optical hyperthermia

Stefano Freddi; Laura Sironi; Rocco D'Antuono; Diego Morone; Alice Donà; Elisa Cabrini; Laura D'Alfonso; Maddalena Collini; Piersandro Pallavicini; Giovanni Baldi; Daniela Maggioni; Giuseppe Chirico

doi:10.1021/nl400129v

A molecular thermometer for nanoparticles for optical hyperthermia

Stefano Freddi, Laura Sironi, Rocco D'Antuono, Diego Morone, Alice Donà, Elisa Cabrini, Laura D'Alfonso, Maddalena Collini, Piersandro Pallavicini, Giovanni Baldi, Daniela Maggioni, Giuseppe Chirico

Istituto Clinico Humanitas

Research output: Contribution to journal › Article

Abstract

We developed an all-optical method to measure the temperature on gold (nanorods and nanostars) and magnetite nanoparticles under near-infrared and radiofrequency excitation by monitoring the excited state lifetime of Rhodamine B that lies within ≅20 nm from the nanoparticle surface. We reached high temperature sensitivity (0.029 ± 0.001 ns/ C) and low uncertainty (±0.3 C). Gold nanostars are ≅3 and ≅100 times more efficient than gold nanorods and magnetite nanoparticles in inducing localized hyperthermia.

Original language	English
Pages (from-to)	2004-2010
Number of pages	7
Journal	Nano Letters
Volume	13
Issue number	5
DOIs	https://doi.org/10.1021/nl400129v
Publication status	Published - May 8 2013

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Keywords

Fluorescence
gold nanoparticles
hyperthermia
near-infrared
thermology

ASJC Scopus subject areas

Condensed Matter Physics
Bioengineering
Chemistry(all)
Materials Science(all)
Mechanical Engineering
Medicine(all)

Cite this

Freddi, S., Sironi, L., D'Antuono, R., Morone, D., Donà, A., Cabrini, E., D'Alfonso, L., Collini, M., Pallavicini, P., Baldi, G., Maggioni, D., & Chirico, G. (2013). A molecular thermometer for nanoparticles for optical hyperthermia. Nano Letters, 13(5), 2004-2010. https://doi.org/10.1021/nl400129v

A molecular thermometer for nanoparticles for optical hyperthermia. / Freddi, Stefano; Sironi, Laura; D'Antuono, Rocco; Morone, Diego; Donà, Alice; Cabrini, Elisa; D'Alfonso, Laura; Collini, Maddalena; Pallavicini, Piersandro; Baldi, Giovanni; Maggioni, Daniela; Chirico, Giuseppe.

In: Nano Letters, Vol. 13, No. 5, 08.05.2013, p. 2004-2010.

Research output: Contribution to journal › Article

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AU - Cabrini, Elisa

AU - D'Alfonso, Laura

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Access to Document

10.1021/nl400129v