A moonshot approach toward the management of cancer patients in the COVID-19 time: What have we learned and what could the Italian network of cancer centers (Alliance against Cancer, ACC) do after the pandemic wave?

Research output: Contribution to journalArticlepeer-review

Abstract

If we focus our attention on seven main features of COVID-19 infection (heterogeneity, fragility, lack of effective treatments and vaccines, "miraculous cures", psychological suffering, deprivation, and globalization), we may establish parallelism with the challenges faced in the steep road to the understanding and treatment of neoplastic diseases. How the similarities between these two conditions can help us cope with the emergency effort represented by the management of cancer patients in the COVID-19 era, today and in the future? In a manner similar to the Cancer Moonshot initiative in the United States, we can hypothesize a multinational moonshot project towards the management of cancer patients during COVID-19 pandemic. In particular, we believe that the main road to elaborate meaningful scientific evidence is represented by the collection of all the data on COVID-19 and cancer comorbidity that are and will become available in cancer centers, coupled with the design of large clinical studies. To address this goal, it is essential to identify the entity that can produce this scientific evidences and the potentially most successful research strategy to undertake. The largest Italian organization for cancer research, Alliance Against Cancer (Alleanza Contro il Cancro, ACC), is called to play a scientific leadership in addressing these challenges, which requires the coordination of oncology teams at regional, national, and international levels. To fulfill this commitment, ACC will create a liaison with health government agencies in order to develop "dynamic"indications able to fight such an unpredictable pandemic. © 2020 The Author(s).
Original languageEnglish
Article number109
JournalJ. Exp. Clin. Cancer Res.
Volume39
Issue number1
DOIs
Publication statusPublished - 2020

Keywords

  • Alliance against Cancer
  • Cancer
  • COVID-19
  • Research
  • Therapy
  • angiotensin converting enzyme 2
  • remdesivir
  • tocilizumab
  • cancer center
  • cancer mortality
  • cancer patient
  • cancer prognosis
  • cancer research
  • cancer therapy
  • comorbidity
  • coronavirus disease 2019
  • disease severity
  • disease transmission
  • health care management
  • health care organization
  • health care personnel
  • health care policy
  • health service
  • human
  • immune response
  • infection control
  • leadership
  • pandemic
  • patient care
  • prevalence
  • priority journal
  • Review
  • serology
  • sex difference
  • social distance
  • social isolation
  • Betacoronavirus
  • complication
  • Coronavirus infection
  • government
  • Italy
  • neoplasm
  • oncology
  • pathogenicity
  • pathology
  • virus pneumonia
  • Coronavirus Infections
  • Government Agencies
  • Humans
  • Medical Oncology
  • Neoplasms
  • Pandemics
  • Pneumonia, Viral

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