A multi-view approach to multi-modal MRI cluster ensembles

Carlos Andrés Méndez, Paul Summers, Gloria Menegaz

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

It has been shown that the combination of multi-modal MRI images improve the discrimination of diseased tissue. However the fusion of dissimilar imaging data for classification and segmentation purposes is not a trivial task, there is an inherent difference in information domains, dimensionality and scales. This work proposes a multiview consensus clustering methodology for the integration of multi-modal MR images into a unified segmentation of tumoral lesions for heterogeneity assessment. Using a variety of metrics and distance functions this multi-view imaging approach calculates multiple vectorial dissimilarity-spaces for each one of the MRI modalities and makes use of the concepts behind cluster ensembles to combine a set of base unsupervised segmentations into an unified partition of the voxel-based data. The methodology is specially designed for combining DCE-MRI and DTI-MR, for which a manifold learning step is implemented in order to account for the geometric constrains of the high dimensional diffusion information.

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
Volume9034
ISBN (Print)9780819498274
DOIs
Publication statusPublished - 2014
EventMedical Imaging 2014: Image Processing - San Diego, CA, United States
Duration: Feb 16 2014Feb 18 2014

Other

OtherMedical Imaging 2014: Image Processing
CountryUnited States
CitySan Diego, CA
Period2/16/142/18/14

Keywords

  • Classification
  • Cluster Ensembles
  • Clustering
  • DCE-MRI
  • DTI-MR
  • Segmentation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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