A multicenter experience on patient and technique survival in children on chronic dialysis

Enrico Verrina, Alberto Edefonti, Bruno Gianoglio, Stefano Rinaldi, Palma Sorino, Graziella Zacchello, Giancarlo Lavoratti, Silvio Maringhini, Carmine Pecoraro, Maria Grazia Calevo, Laura Turrini Dertenois, Francesco Perfumo

Research output: Contribution to journalArticlepeer-review


In this study we compared patient and technique survival of 163 new hemodialysis (HD) patients (age 11.4±3.1 years) and 295 peritoneal dialysis patients (7.7±4.8 years. P<0.001), treated in 23 dialysis centers participating in the Italian Registry of Pediatric Chronic Peritoneal Dialysis (CPD) during the years 1989-2000. Three HD (1.8%) and 17 CPD (5.8%) patients died; the overall average death rate was 9.8/1,000 patient-years in HD and 29.8/1,000 patient-years in CPD patients. No statistically significant difference in patient survival between CPD and HD was found, while the survival of 102 CPD children younger than 5 years at the start of dialysis was lower (P=0.0001) than that of 193 CPD and 160 HD patients aged 5-15 years. We registered 12 modality failures among HD (7.4%) patients and 44 among CPD (14.9%) patients. The main causes were vascular access failure and patient choice in HD, and infection in CPD patients. Technique survival was lower (P=0.007) in CPD than in HD patients; a statistically significant difference (P=0.01) was also observed between both the 0- to 5- and the 5- to 15-year-old CPD patients and the HD patients aged 5-15 years. Logistic regression analysis confirmed age at initiation of dialysis to be a predictor of patient death (P=0.0001) in the whole patient population, and of technique failure in HD (P=0.006) but not in CPD patients (P=0.16).

Original languageEnglish
Pages (from-to)82-90
Number of pages9
JournalPediatric Nephrology
Issue number1
Publication statusPublished - Jan 2004


  • End-stage renal disease
  • Hemodialysis
  • Patient survival
  • Peritoneal dialysis
  • Registry
  • Technique survival

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health


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