A multilayer biomaterial for osteochondral regeneration shows superiority vs microfractures for the treatment of osteochondral lesions in a multicentre randomized trial at 2 years.

Elizaveta Kon, Giuseppe Filardo, Mats Brittberg, Maurizio Busacca, Vincenzo Condello, Lars  Engebretsen, Stefan  Marlovits, Philipp Niemeyer, Patrik  Platzer, Michael  Posthumus, Peter  Verdonk, Renè  Verdonk, Jan Victor, Willem van der Merwe, Wojciech  Widuchowski, Claudio Zorzi, Maurilio Marcacci

Research output: Contribution to journalArticle

Abstract

The increasing awareness on the role of subchondral
bone in the etiopathology of articular surface lesions
led to the development of osteochondral scafolds. While
safety and promising results have been suggested, there
are no trials proving the real potential of the osteochondral
regenerative approach. Aim was to assess the beneft provided
by a nanostructured collagen–hydroxyapatite (collHA)
multilayer scafold for the treatment of chondral and
osteochondral knee lesions.
Original languageEnglish
Pages (from-to)1-12
Number of pages12
JournalKnee Surgery, Sports Traumatology, Arthroscopy
DOIs
Publication statusPublished - Sep 14 2017

Fingerprint

Stress Fractures
Biocompatible Materials
Multicenter Studies
Cartilage
Regeneration
Knee
Joints

Keywords

  • Bone marrow stimulation
  • Cartilage
  • Knee
  • Osteochondral
  • Scaffold

Cite this

A multilayer biomaterial for osteochondral regeneration shows superiority vs microfractures for the treatment of osteochondral lesions in a multicentre randomized trial at 2 years. / Kon, Elizaveta; Filardo, Giuseppe; Brittberg, Mats; Busacca, Maurizio; Condello, Vincenzo; Engebretsen, Lars ; Marlovits, Stefan ; Niemeyer, Philipp; Platzer, Patrik ; Posthumus, Michael ; Verdonk, Peter ; Verdonk, Renè ; Victor, Jan; van der Merwe, Willem; Widuchowski, Wojciech ; Zorzi, Claudio; Marcacci, Maurilio.

In: Knee Surgery, Sports Traumatology, Arthroscopy, 14.09.2017, p. 1-12.

Research output: Contribution to journalArticle

Kon, E, Filardo, G, Brittberg, M, Busacca, M, Condello, V, Engebretsen, L, Marlovits, S, Niemeyer, P, Platzer, P, Posthumus, M, Verdonk, P, Verdonk, R, Victor, J, van der Merwe, W, Widuchowski, W, Zorzi, C & Marcacci, M 2017, 'A multilayer biomaterial for osteochondral regeneration shows superiority vs microfractures for the treatment of osteochondral lesions in a multicentre randomized trial at 2 years.', Knee Surgery, Sports Traumatology, Arthroscopy, pp. 1-12. https://doi.org/10.1007/s00167-017-4707-3
Kon, Elizaveta ; Filardo, Giuseppe ; Brittberg, Mats ; Busacca, Maurizio ; Condello, Vincenzo ; Engebretsen, Lars  ; Marlovits, Stefan  ; Niemeyer, Philipp ; Platzer, Patrik  ; Posthumus, Michael  ; Verdonk, Peter  ; Verdonk, Renè  ; Victor, Jan ; van der Merwe, Willem ; Widuchowski, Wojciech  ; Zorzi, Claudio ; Marcacci, Maurilio. / A multilayer biomaterial for osteochondral regeneration shows superiority vs microfractures for the treatment of osteochondral lesions in a multicentre randomized trial at 2 years. In: Knee Surgery, Sports Traumatology, Arthroscopy. 2017 ; pp. 1-12.
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