A multinational consensus on dysphagia in Parkinson's disease: screening, diagnosis and prognostic value

Giuseppe Cosentino; Micol Avenali; Antonio Schindler; Nicole Pizzorni; Cristina Montomoli; Giovanni Abbruzzese; Angelo Antonini; Filippo Barbiera; Marco Benazzo; Eduardo Elias Benarroch; Giulia Bertino; Emanuele Cereda; Pere Clavè; Pietro Cortelli; Roberto Eleopra; Chiara Ferrari; Shaheen Hamdy; Maggie-Lee Huckabee; Leonardo Lopiano; Rosario Marchese Ragona; Stefano Masiero; Emilia Michou; Antonio Occhini; Claudio Pacchetti; Ronald F Pfeiffer; Domenico A Restivo; Mariangela Rondanelli; Giovanni Ruoppolo; Giorgio Sandrini; Anthony H V Schapira; Fabrizio Stocchi; Eduardo Tolosa; Francesca Valentino; Mauro Zamboni; Roberta Zangaglia; Mario Zappia; Cristina Tassorelli; Enrico Alfonsi

doi:10.1007/s00415-021-10739-8

A multinational consensus on dysphagia in Parkinson's disease: screening, diagnosis and prognostic value

Giuseppe Cosentino, Micol Avenali, Antonio Schindler, Nicole Pizzorni, Cristina Montomoli, Giovanni Abbruzzese, Angelo Antonini, Filippo Barbiera, Marco Benazzo, Eduardo Elias Benarroch, Giulia Bertino, Emanuele Cereda, Pere Clavè, Pietro Cortelli, Roberto Eleopra, Chiara Ferrari, Shaheen Hamdy, Maggie-Lee Huckabee, Leonardo Lopiano, Rosario Marchese RagonaStefano Masiero, Emilia Michou, Antonio Occhini, Claudio Pacchetti, Ronald F Pfeiffer, Domenico A Restivo, Mariangela Rondanelli, Giovanni Ruoppolo, Giorgio Sandrini, Anthony H V Schapira, Fabrizio Stocchi, Eduardo Tolosa, Francesca Valentino, Mauro Zamboni, Roberta Zangaglia, Mario Zappia, Cristina Tassorelli, Enrico Alfonsi

Research output: Contribution to journal › Review article › peer-review

Abstract

BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder characterized by a combination of motor and non-motor dysfunction. Dysphagia is a common symptom in PD, though it is still too frequently underdiagnosed. Consensus is lacking on screening, diagnosis, and prognosis of dysphagia in PD.

OBJECTIVE: To systematically review the literature and to define consensus statements on the screening and the diagnosis of dysphagia in PD, as well as on the impact of dysphagia on the prognosis and quality of life (QoL) of PD patients.

METHODS: A multinational group of experts in the field of neurogenic dysphagia and/or PD conducted a systematic revision of the literature published since January 1990 to February 2021 and reported the results according to PRISMA guidelines. The output of the research was then analyzed and discussed in a consensus conference convened in Pavia, Italy, where the consensus statements were drafted. The final version of statements was subsequently achieved by e-mail consensus.

RESULTS: Eighty-five papers were used to inform the Panel's statements even though most of them were of Class IV quality. The statements tackled four main areas: (1) screening of dysphagia: timing and tools; (2) diagnosis of dysphagia: clinical and instrumental detection, severity assessment; (3) dysphagia and QoL: impact and assessment; (4) prognostic value of dysphagia; impact on the outcome and role of associated conditions.

CONCLUSIONS: The statements elaborated by the Consensus Panel provide a framework to guide the neurologist in the timely detection and accurate diagnosis of dysphagia in PD.

Original language	English
Journal	J. Neurol.
DOIs	https://doi.org/10.1007/s00415-021-10739-8
Publication status	Published - Aug 21 2022

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Cosentino, G., Avenali, M., Schindler, A., Pizzorni, N., Montomoli, C., Abbruzzese, G., Antonini, A., Barbiera, F., Benazzo, M., Benarroch, E. E., Bertino, G., Cereda, E., Clavè, P., Cortelli, P., Eleopra, R., Ferrari, C., Hamdy, S., Huckabee, M-L., Lopiano, L., ... Alfonsi, E. (2022). A multinational consensus on dysphagia in Parkinson's disease: screening, diagnosis and prognostic value. J. Neurol. https://doi.org/10.1007/s00415-021-10739-8

Cosentino, G , Avenali, M, Schindler, A, Pizzorni, N, Montomoli, C, Abbruzzese, G, Antonini, A, Barbiera, F, Benazzo, M, Benarroch, EE, Bertino, G , Cereda, E, Clavè, P, Cortelli, P , Eleopra, R, Ferrari, C, Hamdy, S, Huckabee, M-L, Lopiano, L, Marchese Ragona, R, Masiero, S, Michou, E, Occhini, A , Pacchetti, C, Pfeiffer, RF, Restivo, DA, Rondanelli, M, Ruoppolo, G, Sandrini, G, Schapira, AHV, Stocchi, F, Tolosa, E, Valentino, F, Zamboni, M, Zangaglia, R, Zappia, M, Tassorelli, C & Alfonsi, E 2022, 'A multinational consensus on dysphagia in Parkinson's disease: screening, diagnosis and prognostic value', J. Neurol. https://doi.org/10.1007/s00415-021-10739-8

@article{1e973234baef4e6e84daf7fb39ac38f5,

title = "A multinational consensus on dysphagia in Parkinson's disease: screening, diagnosis and prognostic value",

abstract = "BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder characterized by a combination of motor and non-motor dysfunction. Dysphagia is a common symptom in PD, though it is still too frequently underdiagnosed. Consensus is lacking on screening, diagnosis, and prognosis of dysphagia in PD.OBJECTIVE: To systematically review the literature and to define consensus statements on the screening and the diagnosis of dysphagia in PD, as well as on the impact of dysphagia on the prognosis and quality of life (QoL) of PD patients.METHODS: A multinational group of experts in the field of neurogenic dysphagia and/or PD conducted a systematic revision of the literature published since January 1990 to February 2021 and reported the results according to PRISMA guidelines. The output of the research was then analyzed and discussed in a consensus conference convened in Pavia, Italy, where the consensus statements were drafted. The final version of statements was subsequently achieved by e-mail consensus.RESULTS: Eighty-five papers were used to inform the Panel's statements even though most of them were of Class IV quality. The statements tackled four main areas: (1) screening of dysphagia: timing and tools; (2) diagnosis of dysphagia: clinical and instrumental detection, severity assessment; (3) dysphagia and QoL: impact and assessment; (4) prognostic value of dysphagia; impact on the outcome and role of associated conditions.CONCLUSIONS: The statements elaborated by the Consensus Panel provide a framework to guide the neurologist in the timely detection and accurate diagnosis of dysphagia in PD.",

author = "Giuseppe Cosentino and Micol Avenali and Antonio Schindler and Nicole Pizzorni and Cristina Montomoli and Giovanni Abbruzzese and Angelo Antonini and Filippo Barbiera and Marco Benazzo and Benarroch, {Eduardo Elias} and Giulia Bertino and Emanuele Cereda and Pere Clav{\`e} and Pietro Cortelli and Roberto Eleopra and Chiara Ferrari and Shaheen Hamdy and Maggie-Lee Huckabee and Leonardo Lopiano and {Marchese Ragona}, Rosario and Stefano Masiero and Emilia Michou and Antonio Occhini and Claudio Pacchetti and Pfeiffer, {Ronald F} and Restivo, {Domenico A} and Mariangela Rondanelli and Giovanni Ruoppolo and Giorgio Sandrini and Schapira, {Anthony H V} and Fabrizio Stocchi and Eduardo Tolosa and Francesca Valentino and Mauro Zamboni and Roberta Zangaglia and Mario Zappia and Cristina Tassorelli and Enrico Alfonsi",

note = "{\textcopyright} 2021. The Author(s).",

year = "2022",

month = aug,

day = "21",

doi = "10.1007/s00415-021-10739-8",

language = "English",

journal = "J. Neurol.",

issn = "1432-1459",

}

TY - JOUR

T1 - A multinational consensus on dysphagia in Parkinson's disease

T2 - screening, diagnosis and prognostic value

AU - Cosentino, Giuseppe

AU - Avenali, Micol

AU - Schindler, Antonio

AU - Pizzorni, Nicole

AU - Montomoli, Cristina

AU - Abbruzzese, Giovanni

AU - Antonini, Angelo

AU - Barbiera, Filippo

AU - Benazzo, Marco

AU - Benarroch, Eduardo Elias

AU - Bertino, Giulia

AU - Cereda, Emanuele

AU - Clavè, Pere

AU - Cortelli, Pietro

AU - Eleopra, Roberto

AU - Ferrari, Chiara

AU - Hamdy, Shaheen

AU - Huckabee, Maggie-Lee

AU - Lopiano, Leonardo

AU - Marchese Ragona, Rosario

AU - Masiero, Stefano

AU - Michou, Emilia

AU - Occhini, Antonio

AU - Pacchetti, Claudio

AU - Pfeiffer, Ronald F

AU - Restivo, Domenico A

AU - Rondanelli, Mariangela

AU - Ruoppolo, Giovanni

AU - Sandrini, Giorgio

AU - Schapira, Anthony H V

AU - Stocchi, Fabrizio

AU - Tolosa, Eduardo

AU - Valentino, Francesca

AU - Zamboni, Mauro

AU - Zangaglia, Roberta

AU - Zappia, Mario

AU - Tassorelli, Cristina

AU - Alfonsi, Enrico

PY - 2022/8/21

Y1 - 2022/8/21

N2 - BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder characterized by a combination of motor and non-motor dysfunction. Dysphagia is a common symptom in PD, though it is still too frequently underdiagnosed. Consensus is lacking on screening, diagnosis, and prognosis of dysphagia in PD.OBJECTIVE: To systematically review the literature and to define consensus statements on the screening and the diagnosis of dysphagia in PD, as well as on the impact of dysphagia on the prognosis and quality of life (QoL) of PD patients.METHODS: A multinational group of experts in the field of neurogenic dysphagia and/or PD conducted a systematic revision of the literature published since January 1990 to February 2021 and reported the results according to PRISMA guidelines. The output of the research was then analyzed and discussed in a consensus conference convened in Pavia, Italy, where the consensus statements were drafted. The final version of statements was subsequently achieved by e-mail consensus.RESULTS: Eighty-five papers were used to inform the Panel's statements even though most of them were of Class IV quality. The statements tackled four main areas: (1) screening of dysphagia: timing and tools; (2) diagnosis of dysphagia: clinical and instrumental detection, severity assessment; (3) dysphagia and QoL: impact and assessment; (4) prognostic value of dysphagia; impact on the outcome and role of associated conditions.CONCLUSIONS: The statements elaborated by the Consensus Panel provide a framework to guide the neurologist in the timely detection and accurate diagnosis of dysphagia in PD.

AB - BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder characterized by a combination of motor and non-motor dysfunction. Dysphagia is a common symptom in PD, though it is still too frequently underdiagnosed. Consensus is lacking on screening, diagnosis, and prognosis of dysphagia in PD.OBJECTIVE: To systematically review the literature and to define consensus statements on the screening and the diagnosis of dysphagia in PD, as well as on the impact of dysphagia on the prognosis and quality of life (QoL) of PD patients.METHODS: A multinational group of experts in the field of neurogenic dysphagia and/or PD conducted a systematic revision of the literature published since January 1990 to February 2021 and reported the results according to PRISMA guidelines. The output of the research was then analyzed and discussed in a consensus conference convened in Pavia, Italy, where the consensus statements were drafted. The final version of statements was subsequently achieved by e-mail consensus.RESULTS: Eighty-five papers were used to inform the Panel's statements even though most of them were of Class IV quality. The statements tackled four main areas: (1) screening of dysphagia: timing and tools; (2) diagnosis of dysphagia: clinical and instrumental detection, severity assessment; (3) dysphagia and QoL: impact and assessment; (4) prognostic value of dysphagia; impact on the outcome and role of associated conditions.CONCLUSIONS: The statements elaborated by the Consensus Panel provide a framework to guide the neurologist in the timely detection and accurate diagnosis of dysphagia in PD.

U2 - 10.1007/s00415-021-10739-8

DO - 10.1007/s00415-021-10739-8

M3 - Review article

C2 - 34417870

JO - J. Neurol.

JF - J. Neurol.

SN - 1432-1459

ER -

A multinational consensus on dysphagia in Parkinson's disease: screening, diagnosis and prognostic value

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