TY - JOUR
T1 - A multinational consensus on dysphagia in Parkinson's disease
T2 - screening, diagnosis and prognostic value
AU - Cosentino, Giuseppe
AU - Avenali, Micol
AU - Schindler, Antonio
AU - Pizzorni, Nicole
AU - Montomoli, Cristina
AU - Abbruzzese, Giovanni
AU - Antonini, Angelo
AU - Barbiera, Filippo
AU - Benazzo, Marco
AU - Benarroch, Eduardo Elias
AU - Bertino, Giulia
AU - Cereda, Emanuele
AU - Clavè, Pere
AU - Cortelli, Pietro
AU - Eleopra, Roberto
AU - Ferrari, Chiara
AU - Hamdy, Shaheen
AU - Huckabee, Maggie-Lee
AU - Lopiano, Leonardo
AU - Marchese Ragona, Rosario
AU - Masiero, Stefano
AU - Michou, Emilia
AU - Occhini, Antonio
AU - Pacchetti, Claudio
AU - Pfeiffer, Ronald F
AU - Restivo, Domenico A
AU - Rondanelli, Mariangela
AU - Ruoppolo, Giovanni
AU - Sandrini, Giorgio
AU - Schapira, Anthony H V
AU - Stocchi, Fabrizio
AU - Tolosa, Eduardo
AU - Valentino, Francesca
AU - Zamboni, Mauro
AU - Zangaglia, Roberta
AU - Zappia, Mario
AU - Tassorelli, Cristina
AU - Alfonsi, Enrico
N1 - © 2021. The Author(s).
PY - 2021/8/21
Y1 - 2021/8/21
N2 - BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder characterized by a combination of motor and non-motor dysfunction. Dysphagia is a common symptom in PD, though it is still too frequently underdiagnosed. Consensus is lacking on screening, diagnosis, and prognosis of dysphagia in PD.OBJECTIVE: To systematically review the literature and to define consensus statements on the screening and the diagnosis of dysphagia in PD, as well as on the impact of dysphagia on the prognosis and quality of life (QoL) of PD patients.METHODS: A multinational group of experts in the field of neurogenic dysphagia and/or PD conducted a systematic revision of the literature published since January 1990 to February 2021 and reported the results according to PRISMA guidelines. The output of the research was then analyzed and discussed in a consensus conference convened in Pavia, Italy, where the consensus statements were drafted. The final version of statements was subsequently achieved by e-mail consensus.RESULTS: Eighty-five papers were used to inform the Panel's statements even though most of them were of Class IV quality. The statements tackled four main areas: (1) screening of dysphagia: timing and tools; (2) diagnosis of dysphagia: clinical and instrumental detection, severity assessment; (3) dysphagia and QoL: impact and assessment; (4) prognostic value of dysphagia; impact on the outcome and role of associated conditions.CONCLUSIONS: The statements elaborated by the Consensus Panel provide a framework to guide the neurologist in the timely detection and accurate diagnosis of dysphagia in PD.
AB - BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder characterized by a combination of motor and non-motor dysfunction. Dysphagia is a common symptom in PD, though it is still too frequently underdiagnosed. Consensus is lacking on screening, diagnosis, and prognosis of dysphagia in PD.OBJECTIVE: To systematically review the literature and to define consensus statements on the screening and the diagnosis of dysphagia in PD, as well as on the impact of dysphagia on the prognosis and quality of life (QoL) of PD patients.METHODS: A multinational group of experts in the field of neurogenic dysphagia and/or PD conducted a systematic revision of the literature published since January 1990 to February 2021 and reported the results according to PRISMA guidelines. The output of the research was then analyzed and discussed in a consensus conference convened in Pavia, Italy, where the consensus statements were drafted. The final version of statements was subsequently achieved by e-mail consensus.RESULTS: Eighty-five papers were used to inform the Panel's statements even though most of them were of Class IV quality. The statements tackled four main areas: (1) screening of dysphagia: timing and tools; (2) diagnosis of dysphagia: clinical and instrumental detection, severity assessment; (3) dysphagia and QoL: impact and assessment; (4) prognostic value of dysphagia; impact on the outcome and role of associated conditions.CONCLUSIONS: The statements elaborated by the Consensus Panel provide a framework to guide the neurologist in the timely detection and accurate diagnosis of dysphagia in PD.
U2 - 10.1007/s00415-021-10739-8
DO - 10.1007/s00415-021-10739-8
M3 - Review article
C2 - 34417870
JO - J. Neurol.
JF - J. Neurol.
SN - 1432-1459
ER -