A new FOT set-up for the assessment of respiratory system mechanics in mechanically ventilated infants

Emanuela Zannin, Chiara Veneroni, Valentina Vendettuoli, Piero Matassa, Mariarosa Colnaghi, Antonio Pedotti, Fabio Mosca, Raffaele L. Dellacà

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The assessment of respiratory system mechanics in mechanically ventilated newborns would help in tailoring the ventilatory settings. The Forced Oscillations Technique (FOT) is a non-invasive method for the measurement of the mechanical properties of the respiratory system. The aim of the present work was to develop a measurement set-up suitable to apply FOT in mechanically ventilated newborns. Forced oscillations were generated by a servo-controlled linear motor connected to the inspiratory line of the ventilator. Pressure and flow were measured at the inlet of the tracheal tube and used to compute impedance. The set-up was tested on a mechanical analog of the infant's respiratory system showing good agreement with a traditional FOT set-up. The performance of the system was not influenced by the positive pressures generated by the ventilator. Finally, the system was well tolerated by 5 preterm babies and the measurements allowed to track changes in respiratory mechanics associated to changes in the pressure delivered by the ventilator.

Original languageEnglish
Title of host publication2010 5th Cairo International Biomedical Engineering Conference, CIBEC 2010
Pages49-52
Number of pages4
DOIs
Publication statusPublished - 2010
Event2010 5th Cairo International Biomedical Engineering Conference, CIBEC 2010 - Cairo, Egypt
Duration: Dec 16 2010Dec 18 2010

Other

Other2010 5th Cairo International Biomedical Engineering Conference, CIBEC 2010
CountryEgypt
CityCairo
Period12/16/1012/18/10

Keywords

  • Forced oscillations technique
  • Infants
  • Mechanical ventilation

ASJC Scopus subject areas

  • Biomedical Engineering

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    Zannin, E., Veneroni, C., Vendettuoli, V., Matassa, P., Colnaghi, M., Pedotti, A., Mosca, F., & Dellacà, R. L. (2010). A new FOT set-up for the assessment of respiratory system mechanics in mechanically ventilated infants. In 2010 5th Cairo International Biomedical Engineering Conference, CIBEC 2010 (pp. 49-52). [5716064] https://doi.org/10.1109/CIBEC.2010.5716064