A new liver transplant priority for patients with hepatocellular carcinoma

Matteo Ravaioli, Gian Luca Grazi, Gaetano Vetrone, Takuya Kimura, Matteo Zanello, Giorgio Ercolani, Matteo Cescon, Giovanni Varotti, Massimo del Gaudio, Francesco Tuci, Alessandro Cucchetti, Giuliano La Barba, Marco Vivarelli, Augusto Lauro, Giovanni Ramacciato, Antonio Daniele Pinna

Research output: Contribution to journalArticle

Abstract

Background/Aims: Patients with hepatocellular carcinoma on thei waiting list for liver transplantation are excluded due to causes related to liver failure and tumor progression. We analyze the various factors to suggest a new liver transplant priority. Methodology: We evaluated the outcome on the list of 309 patients with hepatocellular carcinoma and causes of drop-out from the list were divided as death, "too sicle" and tumor progression. The impact of model for end stage liver disease score, tumor stage and waiting time on the causes of drop-outs was evaluated. Results: During the study period, 197 patients had a liver transplantation, 50 were still on the list and the remaining 62 were removed from the list (28 deaths, 30 tumor progressions, and 4 "too sick"). The receiver operating characteristic curves analysis showed that the model for end stage liver disease score predicted the rate of deaths on the list at 1-year (p

Original languageEnglish
Pages (from-to)1742-1745
Number of pages4
JournalHepato-Gastroenterology
Volume55
Issue number86-87
Publication statusPublished - Sep 2008

Keywords

  • Hepatocellular carcinoma
  • Liver transplantation
  • Model for end-stage liver disease score (MELD)
  • Waiting list

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

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  • Cite this

    Ravaioli, M., Grazi, G. L., Vetrone, G., Kimura, T., Zanello, M., Ercolani, G., Cescon, M., Varotti, G., del Gaudio, M., Tuci, F., Cucchetti, A., La Barba, G., Vivarelli, M., Lauro, A., Ramacciato, G., & Pinna, A. D. (2008). A new liver transplant priority for patients with hepatocellular carcinoma. Hepato-Gastroenterology, 55(86-87), 1742-1745.